Bond Destroyers are the opposite of Bond Protectors. These are villains who turn people who are close against each other, be it through lying, trickery, manipulation, possession or brainwashing. Sometimes they can be objects like The One Ring or villains who wish to destroy heroes by separating them through conflict.

Some of these villains destroy friendships and even love, by bringing up dark secrets and revealing things that would cause serious and major conflict between these characters. A key example being Syndrome tricking Mr. Incredible into thinking that Mirage had killed his family, and Helmut Zemo (as shown above), who revealed that the Winter Soldier killed Tony Stark's parents and, along with other factors, caused the Avengers to turn against each other. In some cases, the villains could also destroy bonds that they themselves were involved in, like doing something so awful that causes their family, friends or lovers to turn against or despise them, even if that wasn't their intention.

In the worse case scenario; such revelations can destroy one's innocence and can even cause heroes to descend into villainy, proving just how damaging Bond Destroyers can be. However, there several instances where the victims realize that they were being played and overcome the villain's plan through their close bond.

Examples of villains who destroy other people's bonds include Jagi who ruined Kenshiro and Shin's friendship by tricking Shin into thinking he had to kidnap Kenshiro's girlfriend Yuria to protect her as Kenshiro was too weak to do so, thereby turning one of Kenshiro's closest friends into one of his greatest enemies, Zhan Tiri who destroyed Cassandra and Rapunzel's friendship by showing Cassandra her past and playing with her emotions to get her to turn on Rapunzel, making them become enemies, and Geun-sae who destroyed the Kim and Park families by avenging his wife's death through his murderous rampage. Examples of those who destroy their own bonds are the Kingpin, whose family attempted to flee him and ended up getting killed after learning he was a crime boss, and Blitzø, whose terrible behavior towards others and insecurities caused every person who dated him to despise him.