Route 6 (Japanese: 6番道路Route 6) is a route in western Unova, connecting Driftveil City to Chargestone Cave. It is also the home to Mistralton Cave. The route experiences different weather conditions based on the current season. For example, in the wintertime, it snows.
Several rivers run through the route with many wooden bridges spanning across them. The center of the route houses the Season Research Lab, a facility dedicated to the research of the seasons and how Deerling and Sawsbuck are affected by them.
To the north of the research lab is a house with a woman who will heal the player's Pokémon. The river by the house leads to Mistralton Cave, which is at the east-most side of the route. The entrance to Chargestone Cave is located in the northwest.
The Season Research Lab is a facility dedicated to the research of the seasons, located at the center of the route. As such, there are several Scientists with Deerling in the area.
It also works as a greenhouse, with the scientists cultivating plants inside a glass case by controlling the temperature and humidity. The plants they grow depend on the season. For example, in winter, the glass is hot to the touch and a plant with healthy leaves is growing inside the glass, while in spring, the glass is slightly cold and the scientists are growing some Berries.
A thermometer on the wall shows the current temperature at Route 6, which also varies heavily depending on the season, but varies even within seasons. It can fall as low as −9 °C (15.8 °F) in winter and go as high as 25 °C (77 °F) in spring.
In Black and White, one of the scientists inside the lab requests that the player show him one of each seasonal form of Deerling. When his request is fulfilled, he will give the player a Leaf Stone.
In Black 2 and White 2, one of the scientists inside the lab requests that the player take care of a Deerling with its Hidden Ability, Serene Grace.
A colored background means that the Pokémon can be found in this location in the specified game. A white background with a colored letter means that the Pokémon cannot be found here.
A colored background means that the Pokémon can be found in this location in the specified game. A white background with a colored letter means that the Pokémon cannot be found here.
Two Foongus appear here as fake items. They each have a 50% chance of holding a TinyMushroom, a 25% chance of holding a BigMushroom, and a 1% chance of holding a BalmMushroom. They will respawn every time the player participates in the Funfest Mission "Mushrooms' Hide-and-Seek!".
In A Week to Go and Old Wounds, as Drayden had recently announced that the Pokémon League tournament would be held sooner than originally planned and Black didn't have his eighth Badge yet, Iris suggested that he'd try to catch a rare Legendary Pokémon to impress Drayden. Following Iris's advice, Black went to Mistralton Cave. While Black was inside the cave, Iris met Cedric Juniper. In A Misunderstanding, after Black, Shoko, and Trish had escaped from a fire inside Mistralton Cave, the Swords of Justice took Shoko's Patrat and Trish's Heatmor away. Following their trails, the group quickly located the Swords of Justice. Black managed to convince them to let the Pokémon go, but was dismayed when Iris reminded him that he had just missed an opportunity to catch a rare Legendary Pokémon.
In The Lesson Ends Here, Alder and Marshal encountered N on the route, with N swearing to put an end to the Pokémon League. Seeing N's well-raised Pokémon, Alder suggested a Double Battle, which N accepted. Black, White, and Iris soon discovered the battle, which ended in Alder's defeat, without N even needing to use Zekrom. Cedric Juniper then suddenly entered the scene and urged Black and White to join him in battling against N in order to make him reveal the location of Team Plasma's base, but although they were able to defeat N's Zorua and Tepig, N still managed to get away with Zekrom without revealing the location of the base, with Zorua taking the chance to destroy Cheren's Pokédex, which Cerdic had in his possession, during the escape