Appearing in "Manifest Destiny"
Featured Characters:
- Zero Cochrane (First appearance)
- Avengers (First appearance)
- Captain America (Steve Rogers) (First appearance) (Joins)
- Auntie Maim (First appearance) (Joins)
- Punisher (Jake Gallows) (First appearance) (Joins)
- Doctor Strange (Stephen Strange) (First appearance) (Joins)
- Ikaris (First appearance) (Joins)
- Meanstreak (Henri Huang) (First appearance) (Joins)
- Bloodhawk (Lemuel Krug) (First appearance) (Joins)
- Metalhead (Eddie Osako) (First appearance) (Joins)
- La Lunatica (Luna) (First appearance) (Joins)
- Strange (First appearance) (Joins)
- Moon Knight (First appearance)
- Alchemax (First appearance)
- Gabriel O'Hara (First appearance)
- Xina Kwan-O'Hara (First appearance)
- Board of Directors (First appearance)
- Miguel O'Hara (First appearance) (Leaves Alchemax and joins Avengers)
- Barnett (First appearance)
- Three unnamed directors (First appearance)
- Uatu the Watcher (First appearance; dies)
- Fantastic Four Duplicates (First appearance)
- Mister Fantastic ("Reed Richards") (First appearance)
- Invisible Woman ("Susan Storm") (First appearance)
- Human Torch ("Johnny Storm") (First appearance)
- The Thing ("Ben Grimm") (First appearance) (Joins Avengers)
- Xi'an Chi Xan (First appearance)
Supporting Characters:
- Inhuman Royal Family (First appearance)
- Black Bolt (Blackagar Boltagon) (First appearance) (Joins Avengers)
- Medusa (Medusalith Amaquelin) (First appearance)
- Gorgon Petragon (First appearance)
- Karnak Mander-Azur (First appearance)
- The Lawless (First appearance)
- Reverend (First appearance)
- Mongrel (First appearance)
- Broken Haiku (First appearance)
- Victor Ten Eagles (First appearance)
- Anesthesia Jones (First appearance)
- Krystalin (Ruth Ogada) (First appearance)
- Ghostworks (First appearance)
Other Characters:
- Silver Surfer (Norrin Radd) (First appearance)
- Galactus (Galan) (Mentioned)
- Captain America (President Steve Rogers) (Mentioned)
- Fantastic Four (Mentioned)
- Mister Fantastic (Reed Richards) (Mentioned)
- Invisible Woman (Susan Storm) (Mentioned)
- Human Torch (Johnny Storm) (Mentioned)
- The Thing (Ben Grimm) (Mentioned)
- Khonshu (Mentioned)
- D/Monix (Referenced)
- Conchata O'Hara (Mentioned)
- Goblin (Mentioned)
- Human Torch (Jim Hammond) (Mentioned)
- A.I.M. (Mentioned)
- Hydra (Mentioned)
- Daredevil (Matt Murdock) (First appearance) (Only in flashback)
- Hercules (Only appearance; corpse) (Only in flashback)
- Captain Britain (Brian Braddock) (First appearance) (Only in flashback)
- Sub-Mariner (Namor McKenzie) (First appearance) (Only in flashback)
- Colossus (Piotr Rasputin) (First appearance) (Only in flashback)
- Yondu Udonta (Only appearance; corpse) (Only in flashback)
- Thundra (Only appearance; corpse) (Only in flashback)
- Nightcrawler (Kurt Wagner) (Only appearance; corpse) (Only in flashback)
- Luke Cage (Only appearance; corpse) (Only in flashback)
- Thor Odinson (Mentioned)
- President Doom (Victor von Doom) (Referenced)
- Church of Thor (Mentioned)
- Air-Walker (First appearance)
- Gardener (First appearance)
- Collector (First appearance)
- Stranger (First appearance)
- Mercurio (First appearance)
- Mephisto (First appearance)
- A team similar to the original Avengers (First appearance)
Races and Species:
- Zenn-Lavians
- Humans (Main story and flashback)
- Angels (Mentioned)
- Phalanx (Referenced)
- Watchers
- Mutants (Main story and flashback)
- Werewolves (Mentioned)
- Human-Olympian Hybrids (Only in flashback)
- Human-Otherworlder Hybrids (Only in flashback)
- Atlantean-Human Hybrids (Only in flashback)
- Centaurians (Only in flashback)
- Inhumans
- Eternals
- Atlanteans
- Skrull
- Vrellnexian
- Grund
- Pegasusian
- Kree (Mentioned)
- Shi'ar (Mentioned)
Locations:
- Earth-96943 (First appearance) (Main story and flashback)
- Earth (First appearance) (Main story and flashback)
- United States of America (First appearance) (Main story and flashback)
- Transverse City, Michigan (Mentioned)
- Republic of Free Nebraska (Mentioned)
- Los Angeles, California (Mentioned)
- Idaho (First appearance)
- Lake Pende (First appearance)
- New York (First appearance)
- Newer York (First appearance)
- Manhattan (First appearance)
- Midtown (First appearance)
- Alchemax HQ (First appearance)
- Executive Boardroom (First appearance)
- Doc-in-the-Box (Mentioned)
- Four Freedoms Plaza, 42nd Street and Madison Avenue (Referenced)
- United Nations Headquarters, Turtle Bay (Referenced)
- Daily Bugle Building, 39th Street and Second Avenue, Murray Hill (Referenced)
- Alchemax HQ (First appearance)
- Midtown (First appearance)
- Brooklyn (Mentioned)
- Manhattan (First appearance)
- Newer York (First appearance)
- Earth Orbit (First appearance)
- Moon (First appearance)
- Blue Area of the Moon (First appearance)
- Attilan (First appearance)
- Blue Area of the Moon (First appearance)
- Moon (First appearance)
- Casablanca, Morocco (Referenced)
- Antarctica (First appearance)
- Savage Land (First appearance)
- Xavier City (First appearance)
- Savage Land (First appearance)
- China (Mentioned)
- Latveria (Mentioned)
- Hiroshima, Japan (Mentioned)
- Atlantic Ocean (First appearance)
- Empire of Atlantis (First appearance)
- Atlantis (First appearance)
- Empire of Atlantis (First appearance)
- United States of America (First appearance) (Main story and flashback)
- Heaven (Invoked)
- Earth (First appearance) (Main story and flashback)
- Cyberspace (First appearance)
Items:
- Moon Knight's Suit (First appearance)
- Captain America's Uniform and Shield (First appearance)
- Fantastic Four Uniforms (First appearance)
- Super-Soldier Serum (Mentioned)
- Daredevil's Suit (First appearance) (Only in flashback)
- Captain Britain's Uniform (First appearance) (Only in flashback)
- Mjolnir (First appearance)
- Vita-Rays (Mentioned)
- Punisher's Suit and Arsenal (First appearance)
- Cloak of Levitation and Eye of Agamotto (First appearance)
Synopsis for "Manifest Destiny"
- Synopsis not yet written