ATL-444
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| (IUPAC) ime
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| (1S,3R)-1-[2-(6-amino-9-prop-2-inilpurin-2-ol)etinil]-3-metilcikloheksan-1-ol
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| Klinički podaci
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| Identifikatori
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| ATC kod
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nije dodeljen
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| PubChem[1][2]
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11616539
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| ChemSpider[3]
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9791288
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| Hemijski podaci
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| Formula
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C17H19N5O
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| Mol. masa
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309,365 g/mol
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| SMILES
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eMolekuli & PubHem
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| InChI |
|---|
InChI=1S/C17H19N5O/c1-3-9-22-11-19-14-15(18)20-13(21-16(14)22)6-8-17(23)7-4-5-12(2)10-17/h1,11-12,23H,4-5,7,9-10H2,2H3,(H2,18,20,21)/t12-,17-/m1/s1  Y
Key: VEJLEEFUXFQSHP-SJKOYZFVSA-N Y |
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| Farmakoinformacioni podaci
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| Trudnoća
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?
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| Pravni status
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ATL-444 je lek koji deluje kao potentan i selektivan antagonist adenozinskih receptora A1 i A2A. On se koristi za studiranje uloge adenozinskog receptorskog sistema u pojačavanju dejstva kokaina.[4]
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
- ↑ Doyle, S. E.; Breslin, F. J.; Rieger, J. M.; Beauglehole, A.; Lynch, W. J. (2012). „Time and sex-dependent effects of an adenosine A2A/A1 receptor antagonist on motivation to self-administer cocaine in rats”. Pharmacology Biochemistry and Behavior 102 (2): 257–263. DOI:10.1016/j.pbb.2012.05.001. PMC 3383440. PMID 22579716.
