Jiangsu Hengrui

Jiangsu Hengrui Pharmaceuticals Co. Ltd
Company type	Public company
Traded as	SSE: 600276
Industry	Pharmaceuticals
Founded	1997
Headquarters	Lianyungang, Jiangsu, China
Area served	China; Global;
Key people	Sun Piaoyang (chairman)
Number of employees	24,500 (2020)
Website	www.hrs.com.cn

Jiangsu Hengrui Pharmaceuticals Company Ltd. (Chinese: 江苏恒瑞医药股份有限公司), also known as Jiangsu Hengrui (Chinese: 恒瑞医药), is a Chinese pharmaceutical company that manufactures and distributes various types of drug packaging materials, cancer-treating antineoplastics, cardiovascular medication, painkillers, antibiotics, and related products.^[1]^[2] It is the largest listed pharmaceutical company in China.^[3]

History

Founded in 1970, Jiangsu Hengrui Pharmaceuticals was originally state-owned and called Lianyungang Pharmaceutical Factory (Chinese: 连云港制药厂).^[4]^[5] Headquartered in Lianyungang, Jiangsu, it was established in its current form in 1977. The company was listed on the Shanghai Stock Exchange in 2000^[6] and now has locations in China, the United States, Germany, Switzerland, Japan, and Australia.

Research and development

In 2020, Jiangsu Hengrui Pharmaceuticals set up research and development offices in Princeton, New Jersey, and in Basel, Switzerland.^[7]^[8] The Swiss-based Hengrui Europe Therapeutics AG also hosts the discovery research and development units. Their focus is on protein engineering and the mRNA technology platform.

Since December 2020, Jiangsu Hengrui Pharmaceuticals has run clinical trials on anti-cancer drugs such as:

An anti-PD-1 immune checkpoint inhibitor camrelizumab^[9] for hepatocellular carcinoma;
A nonsteroidal antiandrogen rezvilutamide for prostate cancer;^[10]
A PARP inhibitor fluzoparib^[11] for solid cancers, especially prostate cancer;^[12]
A VEGFR2 inhibitor apatinib as a combination therapy.

Trials were also performed in the fields of metabolic diseases (e.g., type 2 diabetes^[13]), autoimmune diseases (Interleukin-17 receptor blocker vanucizumab in psoriasis), HIV treatment, and analgesia.

References

^ Profile of Jiangsu Hengrui Medicine Company Limited
^ "Search of: Hengrui - List Results - ClinicalTrials.gov". clinicaltrials.gov. Retrieved 22 November 2020.
^ China's pharmaceutical industry is poised for major growth
^ "Sun Piaoyang". Forbes. Retrieved 6 February 2021.
^ "中国最牛"夫妻店"：日赚2亿，一人一家上市公司，掌��2500亿！". finance.sina.cn. 13 December 2020. Archived from the original on 6 February 2021. Retrieved 6 February 2021.
^ "Company Profile". Archived from the original on 28 October 2020. Retrieved 8 January 2020.
^ "Hengrui Medicine sets up clinical research and development in Basel". Basel Area Business & Innovation. Retrieved 22 November 2020.
^ "Entry in commercial registry "Handelsregisteramt des Kantons Basel-Stadt"". www.zefix.ch. Retrieved 22 November 2020.
^ "Search of: camrelizumab - List Results - ClinicalTrials.gov". clinicaltrials.gov. Retrieved 30 December 2020.
^ "Search of: SHR-3680 - List Results - ClinicalTrials.gov". clinicaltrials.gov. Retrieved 30 December 2020.
^ "Search of: SHR-3162 - List Results - ClinicalTrials.gov". clinicaltrials.gov. Retrieved 30 December 2020.
^ "Search of: SHR-3162 - List Results - ClinicalTrials.gov". clinicaltrials.gov. Retrieved 30 December 2020.
^ Jiangsu HengRui Medicine Co., Ltd. (9 December 2020). "Evaluation of the Efficacy and Safety of INS068 Injection and Insulin Degludec Subcutaneous Injection Once Daily in Subjects With Type 2 Diabetes Mellitus Not Adequately Controlled With One or Two Oral Antidiabetics (A Randomized, Open-Label, Two-Arm, Treat-to-Target, Parallel Controlled Trial)". {{cite journal}}: Cite journal requires |journal= (help)

External links

Jiangsu Hengrui Pharmaceuticals Company Limited

[1] Profile of Jiangsu Hengrui Medicine Company Limited

[2] "Search of: Hengrui - List Results - ClinicalTrials.gov". clinicaltrials.gov. Retrieved 22 November 2020.

[3] China's pharmaceutical industry is poised for major growth

[4] "Sun Piaoyang". Forbes. Retrieved 6 February 2021.

[5] "中国最牛"夫妻店"：日赚2亿，一人一家上市公司，掌��2500亿！". finance.sina.cn. 13 December 2020. Archived from the original on 6 February 2021. Retrieved 6 February 2021.

[6] "Company Profile". Archived from the original on 28 October 2020. Retrieved 8 January 2020.

[7] "Hengrui Medicine sets up clinical research and development in Basel". Basel Area Business & Innovation. Retrieved 22 November 2020.

[8] "Entry in commercial registry "Handelsregisteramt des Kantons Basel-Stadt"". www.zefix.ch. Retrieved 22 November 2020.

[9] "Search of: camrelizumab - List Results - ClinicalTrials.gov". clinicaltrials.gov. Retrieved 30 December 2020.

[10] "Search of: SHR-3680 - List Results - ClinicalTrials.gov". clinicaltrials.gov. Retrieved 30 December 2020.

[11] "Search of: SHR-3162 - List Results - ClinicalTrials.gov". clinicaltrials.gov. Retrieved 30 December 2020.

[12] "Search of: SHR-3162 - List Results - ClinicalTrials.gov". clinicaltrials.gov. Retrieved 30 December 2020.

[13] Jiangsu HengRui Medicine Co., Ltd. (9 December 2020). "Evaluation of the Efficacy and Safety of INS068 Injection and Insulin Degludec Subcutaneous Injection Once Daily in Subjects With Type 2 Diabetes Mellitus Not Adequately Controlled With One or Two Oral Antidiabetics (A Randomized, Open-Label, Two-Arm, Treat-to-Target, Parallel Controlled Trial)". {{cite journal}}: Cite journal requires |journal= (help)

[1]

History

Research and development

See also

References

External links