buprenorphine (Q407721)

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opioid used to treat opioid use disorder
  • Buprenex®
  • Temgesic®
  • (-)-buprenorphine
  • 21-cyclopropyl-7alpha-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine
  • 2-(N-cyclopropylmethyl-4,5alpha-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6alpha-yl)-3,3-dimethyl-2-butanol
  • 17-cyclopropylmethyl-4,5alpha-epoxy-7alpha-((S)-1-hydroxy-1,2,2-trimethylpropyl)-6-methoxy-6,14-endo-ethanomorphinan-3-ol
  • 21-cyclopropyl-7α-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine
  • 2-(N-cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6α-yl)-3,3-dimethyl-2-butanol
  • Buprenophine
  • Buprenorphinum
  • (−)-buprenorphine
  • 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(14R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-3,3-dimethyl-2-butanol
  • Buprenorphine
  • 17-cyclopropylmethyl-4,5α-epoxy-7α-((S)-1-hydroxy-1,2,2-trimethylpropyl)-6-methoxy-6,14-endo-ethanomorphinan-3-ol
  • Buprenorfina
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Language Label Description Also known as
default for all languages
No label defined
    English
    buprenorphine
    opioid used to treat opioid use disorder
    • Buprenex®
    • Temgesic®
    • (-)-buprenorphine
    • 21-cyclopropyl-7alpha-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine
    • 2-(N-cyclopropylmethyl-4,5alpha-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6alpha-yl)-3,3-dimethyl-2-butanol
    • 17-cyclopropylmethyl-4,5alpha-epoxy-7alpha-((S)-1-hydroxy-1,2,2-trimethylpropyl)-6-methoxy-6,14-endo-ethanomorphinan-3-ol
    • 21-cyclopropyl-7α-[(S)-1-hydroxy-1,2,2-trimethylpropyl]-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine
    • 2-(N-cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6α-yl)-3,3-dimethyl-2-butanol
    • Buprenophine
    • Buprenorphinum
    • (−)-buprenorphine
    • 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(14R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-3,3-dimethyl-2-butanol
    • Buprenorphine
    • 17-cyclopropylmethyl-4,5α-epoxy-7α-((S)-1-hydroxy-1,2,2-trimethylpropyl)-6-methoxy-6,14-endo-ethanomorphinan-3-ol
    • Buprenorfina

    Statements

    has use
    medication
    0 references
    chemical structure
    Buprenorphin.svg
    333 × 299; 31 KB
    0 references
    Buprenorphine.svg
    580 × 565; 22 KB
    0 references
    mass
    467.304 dalton
    1 reference
    stated in
    PubChem
    PubChem CID
    644073
    language of work or name
    English
    title
    buprenorphine (English)
    retrieved
    18 November 2016
    chemical formula
    C₂₉H₄₁NO₄
    1 reference
    stated in
    PubChem
    PubChem CID
    644073
    language of work or name
    English
    title
    buprenorphine (English)
    retrieved
    18 November 2016
    canonical SMILES
    CC(C)(C)C(C)(C1CC23CCC1(C4C25CCN(C3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)O
    1 reference
    stated in
    PubChem
    PubChem CID
    644073
    language of work or name
    English
    title
    buprenorphine (English)
    retrieved
    18 November 2016
    isomeric SMILES
    C[C@]([C@H]1C[C@@]23CC[C@@]1([C@H]4[C@@]25CCN([C@@H]3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)(C(C)(C)C)O
    1 reference
    stated in
    PubChem
    PubChem CID
    644073
    language of work or name
    English
    title
    buprenorphine (English)
    retrieved
    18 November 2016
    active ingredient in
    Buprenex
    1 reference
    stated in
    RxNorm
    RxNorm ID
    203840
    retrieved
    14 February 2018
    BuTrans
    1 reference
    stated in
    RxNorm
    RxNorm ID
    904871
    retrieved
    14 February 2018
    Probuphine
    1 reference
    stated in
    RxNorm
    RxNorm ID
    1797651
    retrieved
    14 February 2018
    Belbuca
    1 reference
    stated in
    RxNorm
    RxNorm ID
    1716058
    retrieved
    14 February 2018
    significant drug interaction
    legal status (medicine)
    boxed warning
    1 reference
    reference URL
    https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
    title
    FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (English)
    Commons category
    Buprenorphine
    0 references

    Identifiers

    NL CR AUT ID
    ph392394
    subject named as
    buprenorfin
    0 references
    Reaxys registry number
    6182863
    1 reference
    stated in
    ChEBI
    ChEBI ID
    3216
    language of work or name
    English
    title
    buprenorphine (English)
    retrieved
    3 October 2016
    ECHA Substance Infocard ID
    100.052.664
    1 reference
    stated in
    ECHA Substance Infocard database
    ECHA Substance Infocard ID
    100.052.664
    retrieved
    27 December 2018
    title
    Buprenorphine (English)
    quotation
    CAS no.: 52485-79-7 (English)
    MeSH descriptor ID
    D002047
    subject named as
    Buprenorphine
    0 references
    MeSH concept ID
    M0003054
    0 references
    MeSH tree code
    D03.132.577.249.150
    0 references
    D03.605.497.150
    0 references
    D03.633.400.686.150
    0 references
    D04.615.723.795.150
    0 references
    KEGG ID
    C08007
    1 reference
    stated in
    ChEBI
    ChEBI ID
    3216
    language of work or name
    English
    title
    buprenorphine (English)
    retrieved
    3 October 2016
    D07132
    1 reference
    stated in
    ChEBI
    ChEBI ID
    3216
    language of work or name
    English
    title
    buprenorphine (English)
    retrieved
    3 October 2016
    DeCS ID
    2079
    0 references
    NALT ID
    8452
    0 references
    YSO ID
    712
    0 references
     
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