Hypo-phosphorylation of the retinoblastoma protein (pRb) by cyclin D:Cdk4/6 complexes results in active pRb (Q24656289)

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A M Vocero-Akbani

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D R Gius

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M C Wei

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S F Dowdy

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

30 September 1997

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published in

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volume

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issue

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page(s)

10699-704

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cites work

E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry

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Sequences within the conserved cyclin box of human cyclin A are sufficient for binding to and activation of cdc2 kinase

7 April 2017

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Identification of G1 kinase activity for cdk6, a novel cyclin D partner

7 April 2017

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p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

7 April 2017

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The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

7 April 2017

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Growth suppression by p16ink4 requires functional retinoblastoma protein

7 April 2017

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A Restriction Point for Control of Normal Animal Cell Proliferation

7 April 2017

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The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity

7 April 2017

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CDK-independent activation of estrogen receptor by cyclin D1

7 April 2017

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Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

7 April 2017

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Physical interaction of the retinoblastoma protein with human D cyclins

7 April 2017

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The retinoblastoma protein and cell cycle control

7 April 2017

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Evidence for different modes of action of cyclin-dependent kinase inhibitors: p15 and p16 bind to kinases, p21 and p27 bind to cyclins

7 April 2017

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7 April 2017

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Inhibitors of mammalian G1 cyclin-dependent kinases

7 April 2017

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D-type cyclin-dependent kinase activity in mammalian cells

7 April 2017

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Cellular uptake of the tat protein from human immunodeficiency virus

7 April 2017

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The E2F transcription factor is a cellular target for the RB protein

7 April 2017

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Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties

7 April 2017

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A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

7 April 2017

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Temperature-sensitive mutants of p16CDKN2 associated with familial melanoma

7 April 2017

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Negative regulation of cell growth by TGF beta

28 September 2017

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Distinct sub-populations of the retinoblastoma protein show a distinct pattern of phosphorylation

28 September 2017

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Tat-mediated delivery of heterologous proteins into cells

28 September 2017

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DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated in cell-cycle control

28 September 2017

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Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein

28 September 2017

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The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F

28 September 2017

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Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts

28 September 2017

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Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

28 September 2017

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G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23451

Retinoblastoma protein switches the E2F site from positive to negative element

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23451

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.94.20.10699

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

21 January 2018

1 reference

12 December 2020

Independent regulation of human D-type cyclin gene expression during G1 phase in primary human T lymphocytes

1 reference

12 December 2020

Collaboration of G1 cyclins in the functional inactivation of the retinoblastoma protein

1 reference

12 December 2020

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.94.20.10699

1 reference

ADS bibcode

1997PNAS...9410699E

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1 reference

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PubMed publication ID

9380698

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