VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts (Q24302234)

Vascular endothelial growth factor receptor 2

GOA release 2020-03-11

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GOA release 2020-03-11

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Ola Söderberg

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Lena Claesson-Welsh

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Ivana Kholová

object named as

Ivana Kholová

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Bronislaw Pytowski

object named as

Bronislaw Pytowski

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Johan Kreuger

object named as

Johan Kreuger

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author name string

Ingrid Nilsson

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Fuad Bahram

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Xiujuan Li

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Laura Gualandi

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Sina Koch

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Malin Jarvius

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Andrey Anisimov

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Megan Baldwin

Flow cytometric in situ proximity ligation analyses of protein interactions and post-translational modification of the epidermal growth factor receptor family

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language of work or name

English

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publication date

21 April 2010

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1377-88

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cites work

1 reference

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Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor

19 March 2017

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Proteolytic processing regulates receptor specificity and activity of VEGF-C

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Structural determinants of growth factor binding and specificity by VEGF receptor 2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

19 March 2017

1 reference

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A model for gene therapy of human hereditary lymphedema

19 March 2017

1 reference

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The specificity of receptor binding by vascular endothelial growth factor-d is different in mouse and man

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Structural analysis of receptor tyrosine kinases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Characterization of indolinones which preferentially inhibit VEGF-C- and VEGF-D-induced activation of VEGFR-3 rather than VEGFR-2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Cardiovascular failure in mouse embryos deficient in VEGF receptor-3

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Signalling properties of FLT4, a proteolytically processed receptor tyrosine kinase related to two VEGF receptors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

19 March 2017

1 reference

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Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

19 March 2017

1 reference

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Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

19 March 2017

1 reference

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Molecular regulation of angiogenesis and lymphangiogenesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Direct observation of individual endogenous protein complexes in situ by proximity ligation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

VEGF receptor signalling - in control of vascular function

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Order out of chaos: assembly of ligand binding sites in heparan sulfate

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Neuropilin structure governs VEGF and semaphorin binding and regulates angiogenesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

VEGF-C induced angiogenesis preferentially occurs at a distance from lymphangiogenesis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

In situ detection of phosphorylated platelet-derived growth factor receptor beta using a generalized proximity ligation method.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Building blood vessels--stem cell models in vascular biology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Functional interaction of VEGF-C and VEGF-D with neuropilin receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Lymphangiogenesis in development and human disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Roles of vascular endothelial growth factor receptor 3 signaling in differentiation of mouse embryonic stem cell-derived vascular progenitor cells into endothelial cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Involvement of the VEGF receptor 3 in tubular morphogenesis demonstrated with a human anti-human VEGFR-3 monoclonal antibody that antagonizes receptor activation by VEGF-C.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Modulation of VEGFR-2-mediated endothelial-cell activity by VEGF-C/VEGFR-3.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Vascular endothelial growth factor C induces angiogenesis in vivo.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Structure of a VEGF-VEGF receptor complex determined by electron microscopy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Deregulation of Flk-1/vascular endothelial growth factor receptor-2 in fibroblast growth factor receptor-1-deficient vascular stem cell development.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.30

Vascular basement membrane components in angiogenesis--an act of balance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.30

Vascular endothelial growth factor (VEGF)-A165b is a weak in vitro agonist for VEGF receptor-2 due to lack of coreceptor binding and deficient regulation of kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.30

Early Lymph Vessel Development From Embryonic Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.30

Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2868571

Complete and specific inhibition of adult lymphatic regeneration by a novel VEGFR-3 neutralizing antibody

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20224550

12 December 2020

inferred from PubMed ID database lookup

Cooperative and redundant roles of VEGFR-2 and VEGFR-3 signaling in adult lymphangiogenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20224550

12 December 2020

inferred from PubMed ID database lookup

VEGF receptor signal transduction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20224550

12 December 2020

inferred from PubMed ID database lookup

Characterization of indolinones which preferentially inhibit VEGF-C- and VEGF-D-induced activation of VEGFR-3 rather than VEGFR-2

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.30

7 January 2021