REL proto-oncogene, NF-kB subunit (Q21115059)

Immunoglobulin-like fold

1 reference

Proto-oncogene c-Rel

1 reference

Immunoglobulin E-set

1 reference

Rel homology domain (RHD), DNA-binding domain superfamily

1 reference

IPT domain, protein family

1 reference

Rel homology dimerisation domain, protein family

1 reference

Rel homology domain (RHD), DNA-binding domain, protein family

1 reference

NFkappaB IPT domain, protein family

1 reference

Rel homology domain, conserved site, protein family

1 reference

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

sequence-specific DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

chromatin binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

DNA-binding transcription activator activity, RNA polymerase II-specific

2 references

10 September 2018

Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04864&geneProductId=UniProtKB:Q04864

8 April 2019

Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

protein binding

5 references

8 April 2019

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

8 April 2019

Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

8 April 2019

COMMD proteins, a novel family of structural and functional homologs of MURR1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

DNA-binding transcription factor activity

Chromosomal localization of genes encoding the transcription factors, c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10 by fluorescence in situ hybridization

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

DNA-binding transcription factor activity, RNA polymerase II-specific

A census of human transcription factors: function, expression and evolution

3 references

7 November 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04864&geneProductId=UniProtKB:Q04864

NAS

7 November 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04864&geneProductId=UniProtKB:Q04864

Norwegian University of Science and Technology, Systems Biology team

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04864&geneProductId=UniProtKB:Q04864

RNA polymerase II transcription regulatory region sequence-specific DNA binding

ISA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

DNA-binding transcription factor activity, RNA polymerase II-specific

A census of human transcription factors: function, expression and evolution

4 references

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

NAS

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

Norwegian University of Science and Technology, Systems Biology team

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

ISA

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

I-kappaB/NF-kappaB complex

cell component

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04864&geneProductId=UniProtKB:Q04864

1 reference

27 March 2018

transcription regulator complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04864&geneProductId=UniProtKB:Q04864

1 reference

27 March 2018

TAS

nucleus

Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1

4 references

8 April 2019

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

biological process

response to cytokine

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

1 reference

8 April 2019

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

negative regulation of interferon-beta production

1 reference

8 April 2019

Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

negative regulation of gene expression

1 reference

8 April 2019

Nuclear factor κB subunits RelB and cRel negatively regulate Toll-like receptor 3-mediated β-interferon production via induction of transcriptional repressor protein YY1

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04864&geneProductId=UniProtKB:Q04864

1 reference

27 March 2018

positive regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

1 reference

8 April 2019

NIK/NF-kappaB signaling

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

positive regulation of I-kappaB kinase/NF-kappaB signaling

IEP

1 reference

8 April 2019

Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

IEP

innate immune response

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04864&geneProductId=UniProtKB:Q04864

1 reference

27 March 2018

inflammatory response

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

positive regulation of transcription by RNA polymerase II

1 reference

27 March 2018

Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04864&geneProductId=UniProtKB:Q04864

negative regulation of neuron death

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04864

transcription by RNA polymerase II

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04864&geneProductId=UniProtKB:Q04864

I-kappaB kinase/NF-kappaB signaling

positive regulation of transcription by RNA polymerase II

3 references

2 references

1 reference

Rel homology dimerisation domain

1 reference

Rel homology domain, conserved site

1 reference

Rel homology domain (RHD), DNA-binding domain

1 reference

NFkappaB IPT domain

1 reference