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Behave: The Biology of Humans at Our Best and Worst Behave: The Biology of Humans at Our Best and Worst by Robert M. Sapolsky
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“You don’t have to choose between being scientific and being compassionate.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“The brain is heavily influenced by genes. But from birth through young adulthood, the part of the human brain that most defines us (frontal cortex) is less a product of the genes with which you started life than of what life has thrown at you. Because it is the last to mature, by definition the frontal cortex is the brain region least constrained by genes and most sculpted by experience. This must be so, to be the supremely complex social species that we are. Ironically, it seems that the genetic program of human brain development has evolved to, as much as possible, free the frontal cortex from genes.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Why should people in one part of the globe have developed collectivist cultures, while others went individualist? The United States is the individualism poster child for at least two reasons. First there's immigration. Currently, 12 percent of Americans are immigrants, another 12 percent are children of immigrants, and everyone else except for the 0.9 percent pure Native Americans descend from people who emigrated within the last five hundred years. And who were the immigrants? Those in the settled world who were cranks, malcontents, restless, heretical, black sheep, hyperactive, hypomanic, misanthropic, itchy, unconventional, yearning to be rich, yearning to be out of their damn boring repressive little hamlet, yearning. Couple that with the second reason - for the majority of its colonial and independent history, America has had a moving frontier luring those whose extreme prickly optimism made merely booking passage to the New World insufficiently novel - and you've got America the individualistic.
Why has East Asia provided textbook examples of collectivism? The key is how culture is shaped by the way people traditionally made a living, which in turn is shaped by ecology. And in East Asia it's all about rice. Rice, which was domesticated there roughly ten thousand years ago, requires massive amounts of communal work. Not just backbreaking planting and harvesting, which are done in rotation because the entire village is needed to harvest each family's rice. The United States was not without labor-intensive agriculture historically. But rather than solving that with collectivism, it solved it withe slavery.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Morality is simply the attitude we adopt towards people whom we personally dislike.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“In other words, the default state is to trust, and what the amygdala does is learn vigilance and distrust.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Ultimately, forgiveness is usually about one thing—“This is for me, not for you.” Hatred is exhausting; forgiveness, or even just indifference, is freeing. To quote Booker T. Washington, “I shall allow no man to belittle my soul by making me hate him.” Belittle and distort and consume. Forgiveness seems to be at least somewhat good for your health—victims who show spontaneous forgiveness, or who have gone through forgiveness therapy (as opposed to “anger validation therapy”) show improvements in general health, cardiovascular function, and symptoms of depression, anxiety, and PTSD. Chapter 14 explored how compassion readily, perhaps inevitably, contains elements of self-interest. The compassionate granting of forgiveness epitomizes this.41”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“If we accept that there will always be sides, it’s a nontrivial to-do list item to always be on the side of angels. Distrust essentialism. Keep in mind that what seems like rationality is often just rationalization, playing catch-up with subterranean forces that we never suspect. Focus on the larger, shared goals. Practice perspective taking. Individuate, individuate, individuate. Recall the historical lessons of how often the truly malignant Thems keep themselves hidden and make third parties the fall guy. And in the meantime, give the right-of-way to people driving cars with the “Mean people suck” bumper sticker, and remind everyone that we’re all in it together against Lord Voldemort and the House Slytherin.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Testosterone makes people cocky, egocentric, and narcissistic.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“if you’re stressed like a normal mammal in an acute physical crisis, the stress response is lifesaving. But if instead you chronically activate the stress response for reasons of psychological stress, your health suffers. It”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Second, nothing about adolescence can be understood outside the context of delayed frontocortical maturation. If by adolescence limbic, autonomic, and endocrine systems are going full blast while the frontal cortex is still working out the assembly instructions, we’ve just explained why adolescents are so frustrating, great, asinine, impulsive, inspiring, destructive, self-destructive, selfless, selfish, impossible, and world changing. Think about this—adolescence and early adulthood are the times when someone is most likely to kill, be killed, leave home forever, invent an art form, help overthrow a dictator, ethnically cleanse a village, devote themselves to the needy, become addicted, marry outside their group, transform physics, have hideous fashion taste, break their neck recreationally, commit their life to God, mug an old lady, or be convinced that all of history has converged to make this moment the most consequential, the most fraught with peril and promise, the most demanding that they get involved and make a difference. In other words, it’s the time of life of maximal risk taking, novelty seeking, and affiliation with peers. All because of that immature frontal cortex.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“pain makes aggressive people more aggressive, while doing the opposite to unaggressive individuals.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Why is it that our automatic, intuitive moral judgments tend to be nonutilitarian? Because, as Greene states in his book, “Our moral brains evolved to help us spread our genes, not to maximize our collective happiness.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“A remarkably consistent finding, starting with elementary school students, is that males are better at math than females. While the difference is minor when it comes to considering average scores, there is a huge difference when it comes to math stars at the upper extreme of the distribution. For example, in 1983, for every girl scoring in the highest percentile in the math SAT, there were 11 boys.
Why the difference? There have always been suggestions that testosterone is central. During development, testosterone fuels the growth of a brain region involved in mathematical thinking and giving adults testosterone enhances their math skills. Oh, okay, it's biological. But consider a paper published in science in 2008. The authors examined the relationship between math scores and sexual equality in 40 countries based on economic, educational and political indices of gender equality. The worst was Turkey, United States was middling, and naturally, the Scandinavians were tops. Low and behold, the more gender equal the country, the less of a discrepancy in math scores. By the time you get to the Scandinavian countries it's statistically insignificant. And by the time you examine the most gender equal country on earth at the time, Iceland, girls are better at math than boys. Footnote, note that the other reliable sex difference in cognition, namely better reading performance by girls than by boys doesn't disappear in more gender equal societies. It gets bigger. In other words, culture matters. We carry it with us wherever we go.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Things that seem morally obvious and intuitive now weren’t necessarily so in the past; many started with nonconforming reasoning.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Remarkably, studies have examined brains of transgender individuals, concentrating on brain regions that, on the average, differ in size between men and women. And consistently, regardless of the desired direction of the sex change and, in fact, regardless of whether the person had undergone a sex change yet, the dimorphic brain regions in transgender individuals resembled the sex of the person they had always felt themselves to be, not their “actual” sex. In other words, it’s not the case that transgender individuals think they’re a different gender than they actually are. It’s more like they got stuck with the bodies of a different sex from who they actually are.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“We love stress that is mild and transient and occurs in a benevolent context.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“when it comes to empathy and compassion, rich people tend to suck. This has been explored at length in a series of studies by Dacher Keltner of UC Berkeley. Across the socioeconomic spectrum, on the average, the wealthier people are, the less empathy they report for people in distress and the less compassionately they act. Moreover, wealthier people are less adept at recognizing other people’s emotions and in experimental settings are greedier and more likely to cheat or steal. Two of the findings were picked up by the media as irresistible: (a) wealthier people (as assessed by the cost of the car they were driving) are less likely than poor people to stop for pedestrians at crosswalks; (b) suppose there’s a bowl of candy in the lab; invite test subjects, after they finish doing some task, to grab some candy on the way out, telling them that whatever’s left over will be given to some kids—the wealthier take more candy.25 So do miserable, greedy, unempathic people become wealthy, or does being wealthy increase the odds of a person’s becoming that way? As a cool manipulation, Keltner primed subjects to focus either on their socioeconomic success (by asking them to compare themselves with people less well off than them) or on the opposite. Make people feel wealthy, and they take more candy from children.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“How’s this for fascinating: Heritability of various aspects of cognitive development is very high (e.g., around 70 percent for IQ) in kids from high–socioeconomic status (SES) families but is only around 10 percent in low-SES kids. Thus, higher SES allows the full range of genetic influences on cognition to flourish, whereas lower-SES settings restrict them. In other words, genes are nearly irrelevant to cognitive development if you’re growing up in awful poverty—poverty’s adverse effects trump the genetics.fn24 Similarly, heritability of alcohol use is lower among religious than nonreligious subjects—i.e., your genes don’t matter much if you’re in a religious environment that condemns drinking. Domains like these showcase the potential power of classical behavior genetics.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Testosterone also increases confidence and optimism, while decreasing fear and anxiety.5 This explains the “winner” effect in lab animals, where winning a fight increases an animal’s willingness to participate in, and its success in, another such interaction. Part of the increased success probably reflects the fact that winning stimulates testosterone secretion, which increases glucose delivery and metabolism in the animal’s muscles and makes his pheromones smell scarier. Moreover, winning increases the number of testosterone receptors in the bed nucleus of the stria terminalis (the way station through which the amygdala communicates with the rest of the brain), increasing its sensitivity to the hormone. Success in everything from athletics to chess to the stock”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“This leads to a thoroughly fascinating finding—social conservatives tend toward lower thresholds for disgust than liberals.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Priming people to think of God as punitive decreases cheating; thinking of God as forgiving increases it. The researchers then studied subjects from sixty-seven countries, considering the prevalence in each of belief in the existence of a heaven and hell. The greater the skew toward belief in hell, rather than heaven, the lower the national crime rate. When it comes to Eternity, sticks apparently work better than carrots.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“probably the most important fact about genetics and culture is the delayed maturation of the frontal cortex—the genetic programming for the young frontal cortex to be freer from genes than other brain regions, to be sculpted instead by environment, to sop up cultural norms. To hark back to a theme from the first pages of this book, it doesn’t take a particularly fancy brain to learn how to motorically, say, throw a punch. But it takes a fancy, environmentally malleable frontal cortex to learn culture-specific rules about when it’s okay to throw punches.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Testosterone has far less to do with aggression than most assume. Within the normal range, individual differences in testosterone levels don’t predict who will be aggressive. Moreover, the more an organism has been aggressive, the less testosterone is needed for further aggression. When testosterone does play a role, it’s facilitatory—testosterone does not 'invent' aggression. It makes us more sensitive to triggers of aggression. Also, rising testosterone levels foster aggression only during challenges to status. Finally, crucially, the rise in testosterone during a status challenge does not necessarily increase aggression; it increases whatever is needed to maintain status. In a world in which status is awarded for the best of our behaviors, testosterone would be the most prosocial hormone in existence.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Sustained stress has numerous adverse effects. The amygdala becomes overactive and more coupled to pathways of habitual behavior; it is easier to learn fear and harder to unlearn it.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Oxytocin, the luv hormone, makes us more prosocial to Us and worse to everyone else. That’s not generic prosociality. That’s ethnocentrism and xenophobia. In other words, the actions of these neuropeptides depend dramatically on context—who you are, your environment, and who that person is.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Words have power. They can save, cure, uplift, devastate, deflate, and kill. And unconscious priming with words influences pro- and antisocial behaviors.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Archaeologists do something impressive, reflecting disciplinary humility. When archaeologists excavate a site, they recognize that future archaeologists will be horrified at their primitive techniques, at the destructiveness of their excavating. Thus they often leave most of a site untouched to await their more skillful disciplinary descendants. For example, astonishingly, more than forty years after excavations began, less than 1 percent of the famed Qin dynasty terra-cotta army in China has been uncovered.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“A final depressing point about inequality and violence. As we’ve seen, a rat being shocked activates a stress response. But a rat being shocked who can then bite the hell out of another rat has less of a stress response. Likewise with baboons—if you are low ranking, a reliable way to reduce glucocorticoid secretion is to displace aggression onto those even lower in the pecking order. It’s something similar here—despite the conservative nightmare of class warfare, of the poor rising up to slaughter the wealthy, when inequality fuels violence, it is mostly the poor preying on the poor. This point is made with a great metaphor for the consequences of societal inequality.41 The frequency of “air rage”—a passenger majorly, disruptively, dangerously losing it over something on a flight—has been increasing. Turns out there’s a substantial predictor of it: if the plane has a first-class section, there’s almost a fourfold increase in the odds of a coach passenger having air rage. Force coach passengers to walk through first class when boarding, and you more than double the chances further. Nothing like starting a flight by being reminded of where you fit into the class hierarchy. And completing the parallel with violent crime, when air rage is boosted in coach by reminders of inequality, the result is not a crazed coach passenger sprinting into first class to shout Marxist slogans. It’s the guy being awful to the old woman sitting next to him, or to the flight attendant.*”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“In the West we nearly all have strong moral intuitions about the wrongness of slavery, child labor, or animal cruelty. But that sure didn’t used to be the case. Their wrongness has become an implicit moral intuition, a gut instinct concerning moral truth, only because of the fierce moral reasoning (and activism) of those who came before us, when the average person’s moral intuitions were unrecognizably different. Our guts learn their intuitions.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
“Irrational optimism can be great; it’s why only about 15 percent instead of 99 percent of humans get clinically depressed.”
Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst

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