She's a master at hand-to-hand combat and has a track record of fighting hundreds enemies at once
as shown here (shippuden spoiler), and during the Fourth Great Ninja War. Sakura also has Low-Mid regen that scales higher than
Tsunade, and can regenerate from bisection, impalement, and
having her entire midsection gored into. Her strikes also deal internal damage to organs via Scalpel Blade & her Strikes, alongside negating regeneration by
speeding up the death of an opponent's cells with her strikes.
Evasive maneuvering is Sakura's primary go-to.
She has been trained to prioritize evasion over offense, and is proficient enough at evasion to
avoid being hit in blind spots. Having Katsuyu communicating the the location of opponents via Telepathy is another ace she has against this, alongside the problem of being able to summon Katsuyu without much effort.
Check out how big she is!
Unless she has preparation and a way to identify the poison, possibly. She's
removed poisons from people before via Medical Ninjutsu, and has created antidotes to counteract Sasori's poison, which was
stated to be the most deadly of poisons. As it stands, she has three ways to deal with it: Antidotes via Prep, Medical Ninjutsu, and Byakugo.
Being able to cast a Jutsu is reliant on weaving handsigns. Even so, Ninja of her pedigree
can weave handsigns faster than other Ninja can react. Being able to use Jutsu and channel Chakra is not reliant on sound in most cases. And for Sakura, this is not the case.
This is mixed from character to character. Ninja of a lower level do so to align their chakra and/or to be flashy. Naruto doesn't need to say "Rasengan" to make a Rasengan. This is usually for dramatic effect. Muting the verbal component of a Jutsu does not disable the abiity to use Jutsu. Weaving Hand-signs are the only requirement.