The 'Surprised Patrick' or 'Starstruck Patrick' meme, featuring Patrick Star with a shocked expression, is the most iconic image of the character from Spongebob. This image has gained viral popularity as a reaction meme, often inserted into surprising or shocking contexts. It was even used by Nickelodeon for the Kids' Choice Awards promotions in 2015 and 2016.

Patrick Star's memorable moments include an episode where he and SpongeBob attempt to climb a building, with Patrick humorously only a few inches off the ground. In another, he is celebrated by sardines chanting his name and wearing matching outfits. Patrick also stands out when SpongeBob acts unintelligent to make Patrick seem brighter to his parents, and when he successfully passes a driving test, winning a boat.

Humor is subjective, so determining the funniest picture of Patrick Star from Spongebob varies. Notable images include Patrick and Spongebob making a funny face in 'Plankton's Army' and Spongebob's horrified expression in 'Wet Painters'. The Patrick Star gallery on Encyclopedia SpongeBobia also hosts a variety of amusing Patrick images.

Popular Patrick Star images encompass his various roles like Patrick Revere, Pecos Patrick, and Starfish mummy. The 'Surprised Patrick' or 'Starstruck Patrick' image, depicting his surprised face, has gained viral status as a reaction meme, often edited into shocking media scenes. Nickelodeon utilized this meme for Kids' Choice Awards promotions in 2015 and 2016. Images from the 'Educate and Activate' and 'Educate and Activate 2' galleries are also frequently viewed.

Patrick Star once painted a portrait of SpongeBob, which after some alterations, amused both of them. In a different episode, they discovered a giant pencil and used it for drawing. SpongeBob's depiction of a jellyfish, however, received criticism from Patrick for its lack of basic construction and perspective.