- See Sisko for other articles with titles that contain, either by relationship or by coincidence, this character's surname.
- This character is a member of the Sisko family.
Samuel Sisko was a male Human who lived in the 24th century. Sisko was the son of Joseph Sisko and Rebecca Sisko, the brother of Judith Sisko and Aaron Sisko and the half-brother of Benjamin Sisko.
When Samuel was young, his father would send him and his brothers to cultivate the vegetables he grew. (DS9 episode: "Paradise")
In 2381, Sisko returned to New Orleans when his father died. Samuel delivered a eulogy at the memorial for Joseph. (ST - Typhon Pact novel: Rough Beasts of Empire)