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Chemical compound
Iclazepam
7-chloro-1-[2-(cyclopropylmethoxy)ethyl]-5-phenyl-3H -1,4-benzodiazepin-2-one
CAS Number PubChem CID ChemSpider UNII ChEMBL CompTox Dashboard (EPA ) Formula C 21 H 21 Cl N 2 O 2 Molar mass −1 3D model (JSmol )
ClC1=CC2=C(C=C1)N(CCOCC3CC3)C(CN=C2C4=CC=CC=C4)=O
InChI=1S/C21H21ClN2O2/c22-17-8-9-19-18(12-17)21(16-4-2-1-3-5-16)23-13-20(25)24(19)10-11-26-14-15-6-7-15/h1-5,8-9,12,15H,6-7,10-11,13-14H2
Y Key:PLRHQQPBNXIHAZ-UHFFFAOYSA-N
Y (verify)
Iclazepam (Clazepam ) is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, and is around the same potency as chlordiazepoxide .
Iclazepam is a derivative of nordazepam substituted with a cyclopropylmethoxyethyl group on the N 1 nitrogen. Once in the body, iclazepam is quickly metabolised to nordazepam and its N -(2-hydroxyethyl) derivative, which are thought to be mainly responsible for its effects.[ 1]
Alcohols Barbiturates Benzodiazepines Carbamates Flavonoids Imidazoles Kava constituentsMonoureides Neuroactive steroids Nonbenzodiazepines Phenols Piperidinediones Pyrazolopyridines Quinazolinones Volatiles /gases Others/unsorted
3-Hydroxybutanal α-EMTBL AA-29504 Alogabat Avermectins (e.g., ivermectin )Bromide compounds (e.g., lithium bromide , potassium bromide , sodium bromide )Carbamazepine Chloralose Chlormezanone Clomethiazole Darigabat DEABL Deuterated etifoxine Dihydroergolines (e.g., dihydroergocryptine , dihydroergosine , dihydroergotamine , ergoloid (dihydroergotoxine) )DS2 Efavirenz Etazepine Etifoxine Fenamates (e.g., flufenamic acid , mefenamic acid , niflumic acid , tolfenamic acid )Fluoxetine Flupirtine Hopantenic acid KRM-II-81 Lanthanum Lavender oil Lignans (e.g., 4-O-methylhonokiol , honokiol , magnolol , obovatol )Loreclezole Menthyl isovalerate (validolum) Monastrol Niacin Niacinamide Org 25,435 Phenytoin Propanidid Retigabine (ezogabine) Safranal Seproxetine Stiripentol Sulfonylalkanes (e.g., sulfonmethane (sulfonal) , tetronal , trional )Terpenoids (e.g., borneol )Topiramate Valerian constituents (e.g., isovaleric acid , isovaleramide , valerenic acid , valerenol )
