Bakthan Singaram
Notable Accomplishments
UCSC Physical & Biological Sciences Division, Chemistry & Biochemistry Department - Faculty Professor Emerti
Singaram Research Group - Singaram Research Group (SRG) at the University of California, Santa Cruz is headed by Professor Singaram and specializes in Boron-based organic chemistry. A primary goal of the Singaram lab is the development of novel chiral catalysts from terpenes, amino acids, and other biological and organic compounds. Bakthan is an expert in organic synthesis, organoborane chemistry, heterocyclic chemistry, organometallic chemistry, asymmetric synthesis, biosensors, and natural products chemistry.
2012 BORAM-XIII Biennial Awards (0:08:02)
Publications
Amberchan et al.
Binder et al.
Brown et al.
Brown, Herbert C. (1979). "From Little Acorns To Tall Oaks - From Boranes Through Organoboranes (Nobel Lecture)" . Science 210 (4469): 485-492. October 31, 1980. doi:10.1126/science.210.4469.485 . PMID 17841388 . https://www.science.org/doi/10.1126/science.210.4469.485 .
Brown, Herbert C.; Ayyangar, Nagaraj R.; Zweifel, George (1962). "Diisopinocampheylborane as a Reagent for the Production of Optically Active Olefins and the Establishment of Their Configuration" . Journal Of The American Chemical Society 84 (22): 4341–4342. November 1, 1962. doi:10.1021/ja00881a026 . https://pubs.acs.org/doi/10.1021/ja00881a026 .
Brown, Herbert C.; Mead, Edward J.; Rao, B.C. Subra (1955). "A Study Of Solvents For Sodium Borohydride And The Effect Of Solvent And The Metal Ion On Borohydride Reductions" . Journal Of The American Chemical Society . Organic and Biological Chemistry 77 (23): 6209-6213. December 5, 1955. doi:10.1021/ja01628a044 . https://pubs.acs.org/doi/10.1021/ja01628a044 .
Brown, Herbert C.; Schwier, John R.; Singaram, Bakthan (1978). "Simple synthesis of monoisopinocampheylborane of high optical purity" . The Journal of Organic Chemistry 43 (22): 4395–4397. October 1, 1978. doi:10.1021/jo00416a042 . https://pubs.acs.org/doi/abs/10.1021/jo00416a042 .
Brown, Herbert C.; Singaram, Bakthan (1987). "Organoboranes For Synthesis - Substitution With Retention" . Pure And Applied Chemistry 59 (7): 879-894. doi:10.1351/pac198759070879 . https://www.degruyter.com/document/doi/10.1351/pac198759070879/html .
Chrisman et al.
Clary et al.
Clary, Jacob W.; Rettenmaier, Terry J.; Snelling, Rachel; Banwell, Jesse; Wipke, W. Todd; Singaram, Bakthan (2011). "Hydride as a Leaving Group in the Reaction of Pinacolborane with Halides under Ambient Grignard and Barbier Conditions. One-Pot Synthesis of Alkyl, Aryl, Heteroaryl, Vinyl, and Allyl Pinacolboronic Esters" . Journal of Organic Chemistry 76 (23): 9602–9610. November 1, 2011. doi:10.1021/jo201093u . PMID 22040316 . https://pubs.acs.org/doi/10.1021/jo201093u .
Collins et al.
Eagon et al.
Gamsey et al.
Gamsey, Soya (2006). "The Effect Of Boronic Acid-positioning In An Optical Glucose-sensing Ensemble" . Tetrahedron 62 (26): 6321-6331. June 26, 2006. doi:10.1016/j.tet.2006.04.047 . https://www.sciencedirect.com/science/article/abs/pii/S0040402006006454 .
Gamsey, Soya; Miller, Aaron; Olmstead, Marilyn M.; Beavers, Christine M.; Hirayama, Lacie C.; Pradhan, Sulolit; Wessling, Ritchie A.; Singaram, Bakthan (2007). "Boronic Acid-Based Bipyridinium Salts As Tunable Receptors For Monosaccharides And a-Hydroxycarboxylates" . Journal of the American Chemical Society 129 (5): 1278-1286. February 7, 2007. doi:10.1021/ja066567i . https://pubs.acs.org/doi/10.1021/ja066567i .
Goralski et al.
Haddad et al.
Hirayama et al.
Kim et al.
Olmstead et al.
Pasumansky et al.
Pasumansky,, Lubov; Goralski, Christian T.; Singaram, Bakthan (2006). "Lithium Aminoborohydrides: Powerful, Selective, Air-Stable Reducing Agents" . Organic Process Research & Development 10 (5): 959-970. September 2006. doi:10.1021/op0600759 . https://pubs.acs.org/doi/10.1021/op0600759 .
Pasumansky, Lubov; Collins, Christopher J.; Pratt, Lawrence M.; Nguỹên, Ngân Vǎn; Ramachandran, B.; Singaram, Bakthan (2007). "Solvent and Temperature Effects On The Reduction And Amination Reactions Of Electrophiles By Lithium Dialkylaminoborohydrides" . The Journal Of Organic Chemistry 72 (3): 971-976. February 2, 2007. doi:10.1021/jo062154o . PMID 17253818 . https://pubs.acs.org/doi/10.1021/jo062154o .
Pasumansky, Lubov; Haddenham, Dustin; Clary, Jacob W.; Fisher, Gary B.; Goralski, Christian T.; Singaram, Bakthan (2008). "Lithium Aminoborohydrides 16. Synthesis And Reactions Of Monomeric And Dimeric Aminoboranes" . The Journal of Organic Chemistry 73 (5): 1898-1905. March 7, 2008. doi:10.1021/jo702271c . PMID 18215062 . https://pubs.acs.org/doi/10.1021/jo702271c .
Schiller et al.
Schiller, Alexander; Vilozny, Boaz; Wessling, Ritchie A.; Singaram, Bakthan (2008). "Recognition Of Phospho Sugars And Nucleotides With An Array Of Boronic Acid Appended Bipyridinium Salts" . Analytica Chimica Acta 627 (2). October 10, 2008. doi:10.1016/j.aca.2008.08.011 . PMID 18809074 . https://www.sciencedirect.com/science/article/abs/pii/S0003267008014888?via%3Dihub .
Schiller, Alexander; Wessling, Ritchie A.; Singarum, Bakthan (2007). "A Fluorescent Sensor Array For Saccharides Based On Boronic Acid Appended Bipyridinium Salts" . Angewandte Chemie, International Edition 46 (34): 6457-6459. August 27, 2007. doi:10.1002/anie.200701888 . PMID 17654643 . https://onlinelibrary.wiley.com/doi/10.1002/anie.200701888 .
Sharrett et al.
Sharrett, Zachary; Gamsey, Soya; Fat, Jonathan; Cunningham-Bryant, Daniel; Wessling, Ritchie A.; Singaram, Bakthan (2007). "The Effect Of Boronic Acid Acidity On Performance Of Viologen-based Boronic Acids In A Two-component Optical Glucose-sensing System" . Tetrahedron Letters 48 (29): 5125-5129. July 16, 2007. doi:10.1016/j.tetlet.2007.05.075 . https://www.sciencedirect.com/science/article/abs/pii/S0040403907009422 .
Sharrett, Zachary; Gamsey, Soya; Levine, Paul; Cunningham-Bryant, Dan; Vilozny, Boaz; Schiller, Alexander; Wessling, Ritchie A.; Singaram, Bakthan (2008). "Boronic Acid-appended bis-Viologens As A New Family Of Viologen Quenchers For Glucose Sensing" . Tetrahedron Letters 49 (2): 300-304. January 7, 2008. doi:10.1016/j.tetlet.2007.11.053 . https://www.sciencedirect.com/science/article/abs/pii/S004040390702237X .
Steiner et al.
TarBX Reactions
LAB Reactions
Glucose Sensing Quencher-Dye System
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