PWP1

PWP1
Identifiers
Aliases	PWP1, IEF-SSP-9502, PWP1 homolog, endonuclein
External IDs	MGI: 1914735; HomoloGene: 5129; GeneCards: PWP1; OMA:PWP1 - orthologs
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	85,724,960 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; nipple; ; pylorus; ; cardia; ; renal medulla; ; pericardium; ; Achilles tendon; ; vulva; ; pons; ; parietal pleura;
	Top expressed in
	primitive streak; ; abdominal wall; ; endothelial cell of lymphatic vessel; ; Paneth cell; ; spermatocyte; ; epiblast; ; medial ganglionic eminence; ; morula; ; hair follicle; ; maxillary prominence;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	H4K20me3 modified histone binding;
Cellular component	nucleus; Golgi apparatus; nucleolus; chromosome;
Biological process	transcription, DNA-templated; positive regulation of stem cell differentiation; histone H4-K20 trimethylation; negative regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of transcription of nucleolar large rRNA by RNA polymerase I; ribosome biogenesis;
	Sources:Amigo / QuickGO
Orthologs
	11137
	103136
	n/a
	ENSMUSG00000001785
	Q13610
	Q99LL5
	NM_007062; NM_001317962; NM_001317963
	NM_133993
	NP_001304891; NP_001304892; NP_008993
	NP_598754
	Wikidata
View/Edit Human	View/Edit Mouse

Periodic tryptophan protein 1 homolog is a protein that in humans is encoded by the PWP1 gene.^[4]^[5]

References

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000001785 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Honore B, Leffers H, Madsen P, Celis JE (Feb 1995). "Cloning of a cDNA encoding a novel human nuclear phosphoprotein belonging to the WD-40 family". Gene. 151 (1–2): 291–6. doi:10.1016/0378-1119(94)90673-4. PMID 7828893.
^ "Entrez Gene: PWP1 PWP1 homolog (S. cerevisiae)".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Gress TM, M��ller-Pillasch F, Geng M, et al. (1996). "A pancreatic cancer-specific expression profile". Oncogene. 13 (8): 1819–30. PMID 8895530.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
Honoré B, Baandrup U, Nielsen S, Vorum H (2002). "Endonuclein is a cell cycle regulated WD-repeat protein that is up-regulated in adenocarcinoma of the pancreas". Oncogene. 21 (7): 1123–9. doi:10.1038/sj.onc.1205186. PMID 11850830. S2CID 1657629.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000001785 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7828893-4] Honore B, Leffers H, Madsen P, Celis JE (Feb 1995). "Cloning of a cDNA encoding a novel human nuclear phosphoprotein belonging to the WD-40 family". Gene. 151 (1–2): 291–6. doi:10.1016/0378-1119(94)90673-4. PMID 7828893.

[entrez-5] "Entrez Gene: PWP1 PWP1 homolog (S. cerevisiae)".

[4]

PWP1

References

Further reading