NLE1

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Notchless protein homolog 1 is a protein that in humans is encoded by the NLE1 gene.^[5]

NLE1

Identifiers

NLE1, Nle, notchless homolog 1

External IDs

MGI: 2429770; HomoloGene: 5494; GeneCards: NLE1; OMA:NLE1 - orthologs

Gene location (Human)

Chr.	Chromosome 17 (human)^[1]

Band	17q12	Start	35,128,730 bp^[1]
Band	17q12	End	35,142,304 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 11 (mouse)^[2]

Band	11\|11 C	Start	82,791,594 bp^[2]
Band	11\|11 C	End	82,799,237 bp^[2]

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

gonad

body of pancreas

ganglionic eminence

ventricular zone

stromal cell of endometrium

left ovary

prefrontal cortex

muscle of thigh

gastrocnemius muscle

right ovary

Top expressed in

morula

yolk sac

epiblast

embryo

neural layer of retina

ventricular zone

blastocyst

muscle of thigh

embryo

lip

More reference expression data


More reference expression data

Species

Human

Mouse


54475


217011


ENSG00000073536


ENSMUSG00000020692


Q9NVX2


Q8VEJ4

RefSeq (mRNA)


NM_001014445 NM_018096


NM_145431

RefSeq (protein)


NP_001014445 NP_060566


NP_663406

Location (UCSC)

Chr 17: 35.13 – 35.14 Mb

Chr 11: 82.79 – 82.8 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000073536 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020692 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: NLE1 notchless homolog 1 (Drosophila)".

Further reading

Stanchi F, Bertocco E, Toppo S, et al. (2001). "Characterization of 16 novel human genes showing high similarity to yeast sequences". Yeast. 18 (1): 69–80. doi:10.1002/1097-0061(200101)18:1<69::AID-YEA647>3.0.CO;2-H. PMID 11124703. S2CID 21397515.
Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

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