VIPR1

VIPR1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1OF2, 1OGT, 3B3I, 3B6S, 3DTX, 3HCV, 5DEF, 5DEG
Dynodwyr
Cyfenwau	VIPR1, HVR1, II, PACAP-R-2, PACAP-R2, RDC1, V1RG, VAPC1, VIP-R-1, VIPR, VIRG, VPAC1, VPAC1R, VPCAP1R, vasoactive intestinal peptide receptor 1
Dynodwyr allanol	OMIM: 192321 HomoloGene: 3399 GeneCards: VIPR1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transmembrane signaling receptor activity • signal transducer activity • G protein-coupled receptor activity • GO:0001948, GO:0016582 protein binding • vasoactive intestinal polypeptide receptor activity • peptide hormone binding • G protein-coupled peptide receptor activity Cydrannau o'r gell • Cellbilen • bilen • integral component of membrane • receptor complex • integral component of plasma membrane Prosesau biolegol • cell surface receptor signaling pathway • positive regulation of cell population proliferation • G protein-coupled receptor signaling pathway • GO:0072468 signal transduction • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7433	n/a
Ensembl	ENSG00000114812	n/a
UniProt	P32241	n/a
RefSeq (mRNA)	NM_001251882 NM_001251883 NM_001251884 NM_001251885 NM_004624	n/a
RefSeq (protein)	NP_001238811 NP_001238812 NP_001238813 NP_001238814 NP_004615	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn VIPR1 yw VIPR1 a elwir hefyd yn Vasoactive intestinal polypeptide receptor 1 a Vasoactive intestinal peptide receptor 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3p22.1.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn VIPR1.

• "Spatial proximity between the VPAC1 receptor and the amino terminus of agonist and antagonist peptides reveals distinct sites of interaction. ". FASEB J. 2012. PMID 22291440.
• "Gender-dependent association of type 2 diabetes with the vasoactive intestinal peptide receptor 1. ". Gene. 2012. PMID 22166542.
• "The SNP rs9677 of VPAC1 gene is associated with glycolipid control and heart function in female patients with type 2 diabetes: A follow-up study. ". Nutr Metab Cardiovasc Dis. 2016. PMID 26712708.
• "VPAC1 overexpression is associated with poor differentiation in colon cancer. ". Tumour Biol. 2014. PMID 24671823.
• "VPAC1 receptor expression in peripheral blood mononuclear cells in a human endotoxemia model.". J Transl Med. 2013. PMID 23651810.