TNFRSF13B

TNFRSF13B
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1XU1, 1XUT
Dynodwyr
Cyfenwau	TNFRSF13B, CD267, CVID, CVID2, RYZN, TACI, TNFRSF14B, IGAD2, tumor necrosis factor receptor superfamily member 13B, TNF receptor superfamily member 13B
Dynodwyr allanol	OMIM: 604907 HomoloGene: 49320 GeneCards: TNFRSF13B
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • signaling receptor activity Cydrannau o'r gell • integral component of membrane • integral component of plasma membrane • bilen • Cellbilen Prosesau biolegol • cell surface receptor signaling pathway • tumor necrosis factor-mediated signaling pathway • adaptive immune response • immune system process • B cell homeostasis • hematopoietic progenitor cell differentiation • negative regulation of B cell proliferation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23495	n/a
Ensembl	ENSG00000240505	n/a
UniProt	O14836	n/a
RefSeq (mRNA)	NM_012452	n/a
RefSeq (protein)	NP_036584	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TNFRSF13B yw TNFRSF13B a elwir hefyd yn TNF receptor superfamily member 13B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17p11.2.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TNFRSF13B.

• "TNF receptor superfamily member 13b (TNFRSF13B) hemizygosity reveals transmembrane activator and CAML interactor haploinsufficiency at later stages of B-cell development. ". J Allergy Clin Immunol. 2015. PMID 26100089.
• "Genetics of common variable immunodeficiency: role of transmembrane activator and calcium modulator and cyclophilin ligand interactor. ". Int J Immunogenet. 2015. PMID 26096648.
• "Clinical Associations of Biallelic and Monoallelic TNFRSF13B Variants in Italian Primary Antibody Deficiency Syndromes. ". J Immunol Res. 2016. PMID 27123465.
• "Incidence of the C104R TACI Mutation in Patients With Primary Antibody Deficiency. ". J Investig Allergol Clin Immunol. 2015. PMID 26727773.
• "Application of diagnostic and treatment criteria for common variable immunodeficiency disorder.". Expert Rev Clin Immunol. 2016. PMID 26623716.