SDCBP

SDCBP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1N99, 1NTE, 1OBX, 1OBY, 1OBZ, 1R6J, 1V1T, 1W9E, 1W9O, 1W9Q, 1YBO, 4Z33
Dynodwyr
Cyfenwau	SDCBP, MDA-9, ST1, SYCL, TACIP18, MDA9, syndecan binding protein
Dynodwyr allanol	OMIM: 602217 HomoloGene: 4110 GeneCards: SDCBP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein N-terminus binding • GO:0005110 frizzled binding • GO:0001948, GO:0016582 protein binding • identical protein binding • cytoskeletal anchor activity • interleukin-5 receptor binding • phosphatidylinositol-4,5-bisphosphate binding • lipid binding • cadherin binding • syndecan binding • protein heterodimerization activity Cydrannau o'r gell • cytoplasm • extracellular vesicle • blood microparticle • endoplasmic reticulum membrane • bilen • focal adhesion • melanosome • adherens junction • Cellbilen • cell junction • Reticwlwm endoplasmig • membrane raft • extracellular exosome • Cytosgerbwd • cnewyllyn cell • extracellular region • extracellular space • nucleoplasm • cytosol • interleukin-5 receptor • nuclear membrane • azurophil granule lumen • intracellular membrane-bounded organelle Prosesau biolegol • positive regulation of transforming growth factor beta receptor signaling pathway • GO:0007243 intracellular signal transduction • positive regulation of extracellular exosome assembly • negative regulation of receptor internalization • protein targeting to membrane • ephrin receptor signaling pathway • substrate-dependent cell migration, cell extension • positive regulation of pathway-restricted SMAD protein phosphorylation • positive regulation of JNK cascade • positive regulation of epithelial to mesenchymal transition • regulation of mitotic cell cycle • negative regulation of proteasomal ubiquitin-dependent protein catabolic process • positive regulation of exosomal secretion • positive regulation of phosphorylation • actin cytoskeleton organization • chemical synaptic transmission • positive regulation of cell population proliferation • positive regulation of cell growth • positive regulation of cell migration • neutrophil degranulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6386	n/a
Ensembl	ENSG00000137575	n/a
UniProt	O00560	n/a
RefSeq (mRNA)	NM_001007067 NM_001007068 NM_001007069 NM_001007070 NM_005625 NM_001330537 NM_001348339 NM_001348340 NM_001348341	n/a
RefSeq (protein)	NP_001007068 NP_001007069 NP_001007070 NP_001007071 NP_001317466 NP_005616 NP_001335268 NP_001335269 NP_001335270	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SDCBP yw SDCBP a elwir hefyd yn Syndecan binding protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 8, band 8q12.1.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SDCBP.

• "MDA-9/syntenin is a key regulator of glioma pathogenesis. ". Neuro Oncol. 2014. PMID 24305713.
• "Novel role of MDA-9/syntenin in regulating urothelial cell proliferation by modulating EGFR signaling. ". Clin Cancer Res. 2013. PMID 23873690.
• "Examination of Epigenetic and other Molecular Factors Associated with mda-9/Syntenin Dysregulation in Cancer Through Integrated Analyses of Public Genomic Datasets. ". Adv Cancer Res. 2015. PMID 26093898.
• "Syntenin and syndecan in the biogenesis of exosomes. ". Biol Cell. 2015. PMID 26032692.
• "Targeting tumor invasion: the roles of MDA-9/Syntenin.". Expert Opin Ther Targets. 2015. PMID 25219541.