RBBP7

RBBP7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3CFS, 3CFV
Dynodwyr
Cyfenwau	RBBP7, RbAp46, retinoblastoma binding protein 7, RB binding protein 7, chromatin remodeling factor
Dynodwyr allanol	OMIM: 300825 HomoloGene: 55702 GeneCards: RBBP7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • RNA binding • histone deacetylase activity Cydrannau o'r gell • NuRD complex • ESC/E(Z) complex • cnewyllyn cell • nucleoplasm • cytosol Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • response to steroid hormone • cellular heat acclimation • GO:1901227 negative regulation of transcription by RNA polymerase II • GO:0061641 CENP-A containing chromatin assembly • transcription, DNA-templated • multicellular organism development • DNA replication • negative regulation of gene expression, epigenetic • negative regulation of cell growth • cell population proliferation • GO:0045996 negative regulation of transcription, DNA-templated • regulation of signal transduction by p53 class mediator • histone deacetylation • post-translational protein modification • negative regulation of G0 to G1 transition • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5931	n/a
Ensembl	ENSG00000102054	n/a
UniProt	Q16576	n/a
RefSeq (mRNA)	NM_001198719 NM_002893	n/a
RefSeq (protein)	NP_001185648 NP_002884	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RBBP7 yw RBBP7 a elwir hefyd yn RB binding protein 7, chromatin remodeling factor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom X dynol, band Xp22.2.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RBBP7.

• RbAp46

• "Inducible expression of RbAp46 activates c-Jun NH2-terminal kinase-dependent apoptosis and suppresses progressive growth of tumor xenografts in nude mice. ". Anticancer Res. 2003. PMID 14981905.
• "Rb-associated protein 46 (RbAp46) inhibits transcriptional transactivation mediated by BRCA1. ". Biochem Biophys Res Commun. 2001. PMID 11394910.
• "Discovery of retinoblastoma-associated binding protein 46 as a novel prognostic marker for distant metastasis in nonsmall cell lung cancer by combined analysis of cancer cell secretome and pleural effusion proteome. ". J Proteome Res. 2009. PMID 19655816.
• "Constitutive expression of Rb associated protein 46 (RbAp46) reverts transformed phenotypes of breast cancer cells. ". Anticancer Res. 2003. PMID 14666671.
• "Expression, purification and characterization of the human MTA2-RBBP7 complex.". Biochim Biophys Acta. 2017. PMID 28179136.