PDLIM1

PDLIM1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1X62, 2PKT
Dynodwyr
Cyfenwau	PDLIM1, CLIM1, CLP-36, CLP36, HEL-S-112, hCLIM1, PDZ and LIM domain 1
Dynodwyr allanol	OMIM: 605900 HomoloGene: 9643 GeneCards: PDLIM1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001105 transcription coactivator activity • metal ion binding • cadherin binding involved in cell-cell adhesion • actin binding • muscle alpha-actinin binding Cydrannau o'r gell • cytoplasm • Cytosgerbwd • focal adhesion • transcription regulator complex • Z discdkac • stress fiber • filamentous actin Prosesau biolegol • response to hypoxia • GO:0009373 regulation of transcription, DNA-templated • GO:0001306 response to oxidative stress • cell-cell adhesion • positive regulation of nucleic acid-templated transcription • heart development • actin cytoskeleton organization • muscle structure development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9124	n/a
Ensembl	ENSG00000107438	n/a
UniProt	O00151	n/a
RefSeq (mRNA)	NM_020992	n/a
RefSeq (protein)	NP_066272	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PDLIM1 yw PDLIM1 a elwir hefyd yn PDZ and LIM domain 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 10, band 10q23.33.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PDLIM1.

• "Characterization of the human 36-kDa carboxyl terminal LIM domain protein (hCLIM1). ". J Cell Biochem. 1999. PMID 10022510.
• "Autoantibodies against TYMS and PDLIM1 proteins detected as circulatory signatures in Indian breast cancer patients. ". Proteomics Clin Appl. 2016. PMID 27068564.
• "PDZ and LIM domain protein 1(PDLIM1)/CLP36 promotes breast cancer cell migration, invasion and metastasis through interaction with α-actinin. ". Oncogene. 2015. PMID 24662836.
• "Femtomolar Zn2+ affinity of LIM domain of PDLIM1 protein uncovers crucial contribution of protein-protein interactions to protein stability. ". J Inorg Biochem. 2012. PMID 22922308.
• "Expression of the actin stress fiber-associated protein CLP36 in the human placenta.". Histochem Cell Biol. 2006. PMID 16609848.