COPS4

COPS4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4D0P, 4D10, 4D18, 4WSN
Dynodwyr
Cyfenwau	COPS4, CSN4, COP9 signalosome subunit 4, SGN4
Dynodwyr allanol	OMIM: 616008 HomoloGene: 8067 GeneCards: COPS4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • NEDD8-specific protease activity Cydrannau o'r gell • cytoplasm • COP9 signalosome • cell junction • synapse • extracellular exosome • GO:0016023 cytoplasmic vesicle • synaptic vesicle • cnewyllyn cell • nucleoplasm • cytosol • nuclear speck Prosesau biolegol • transcription-coupled nucleotide-excision repair • nucleotide-excision repair, DNA damage recognition • protein deneddylation • post-translational protein modification Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	51138	n/a
Ensembl	ENSG00000138663	n/a
UniProt	Q9BT78	n/a
RefSeq (mRNA)	NM_001258006 NM_016129 NM_001330727	n/a
RefSeq (protein)	NP_001244935 NP_001317656 NP_057213	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn COPS4 yw COPS4 a elwir hefyd yn COP9 signalosome complex subunit 4 a COP9 signalosome subunit 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 4, band 4q21.22.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn COPS4.

• CSN4
• SGN4

• "COP9 signalosome-directed c-Jun activation/stabilization is independent of JNK. ". J Biol Chem. 1999. PMID 10585392.
• "COP9 subunits 4 and 5 target soluble guanylyl cyclase α1 and p53 in prostate cancer cells. ". Mol Endocrinol. 2014. PMID 24725084.
• "COP9 signalosome revisited: a novel mediator of protein degradation. ". Trends Cell Biol. 2001. PMID 11567875.
• "Aberrant expression of signaling-related proteins 14-3-3 gamma and RACK1 in fetal Down syndrome brain (trisomy 21). ". Electrophoresis. 2002. PMID 11824616.
• "Interaction between interferon consensus sequence-binding protein and COP9/signalosome subunit CSN2 (Trip15). A possible link between interferon regulatory factor signaling and the COP9/signalosome.". J Biol Chem. 2000. PMID 10991940.