File:Differentiation of Human-Induced Pluripotent Stem Cells to GABAergic Neurons.tif

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Differentiation of Human-Induced Pluripotent Stem Cells to GABAergic Neurons

Summary

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Description
Українська: Флуоресцентна мікроскопія культури нейронів переднього мозку після 40 днів диференціації від індукованих людських плюрипотентних стовбурових клітин (iPSCs). iPSCs від пацієнтки з сімейною формою хвороби Альцгеймера, мутація у гені PSEN1.

TUJ-1-позитивні клітини експресують маркер (β3-tubulin) зрілих нейронів (червоний колір).

GABA-позитивні клітини (зелений колір) експресують маркер GABA- ергічних нейронів - рецептор гамма-аміномасляної кислоти (ГАМК) A, альфа 1.

Ядра клітин пофарбовані DAPI (синій колір).

Збільшення 40 Х.
English: Fluorescence microscopy of forebrain neuronal culture after 40 days of differentiation from induced human pluripotent stem cells (iPSCs). iPSCs from a patient with familial Alzheimer's disease, a mutation in the PSEN1 gene.

TUJ-1-positive cells express a marker (β3-tubulin) of mature neurons (red).

GABA-positive cells (green) express a marker of GABAergic neurons - gamma-aminobutyric acid (GABA) receptor A, alpha 1.

Cell nuclei are stained with DAPI (blue).

Magnification 40X.
Date
Source Own work
Author Morozless

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 This image was uploaded as part of Science Photo Competition 2023 in Ukraine.

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current12:58, 20 December 2023Thumbnail for version as of 12:58, 20 December 20231,296 × 966 (3.58 MB)Morozless (talk | contribs)Uploaded own work with UploadWizard

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