Antagonists of the receptor-G protein interface block Gi-coupled signal transduction. (Q32061869)

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12 November 2019

title

Antagonists of the receptor-G protein interface block Gi-coupled signal transduction (English)

1 reference

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G protein-coupled receptor

12 November 2019

main subject

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12 November 2019

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12 November 2019

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12 November 2019

B Dineen

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12 November 2019

A Dice

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12 November 2019

J Linden

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12 November 2019

W R Proctor

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12 November 2019

T V Dunwiddie

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12 November 2019

H E Hamm

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12 November 2019

language of work or name

English

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publication date

1 June 1998

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Journal of Biological Chemistry

12 November 2019

published in

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12 November 2019

volume

273

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issue

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12 November 2019

page(s)

14912-14919

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Three cytoplasmic loops of rhodopsin interact with transducin

12 November 2019

cites work

1 reference

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The thrombin receptor second cytoplasmic loop confers coupling to Gq-like G proteins in chimeric receptors. Additional evidence for a common transmembrane signaling and G protein coupling mechanism in G protein-coupled receptors

21 January 2018

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Identification of receptor contact site involved in receptor-G protein coupling

21 January 2018

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Receptor and effector interactions of Gs. Functional studies with antibodies to the alpha s carboxyl-terminal decapeptide

21 January 2018

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Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha

21 January 2018

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Potent peptide analogues of a G protein receptor-binding region obtained with a combinatorial library

21 January 2018

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Diversity and selectivity of receptor-G protein interaction

21 January 2018

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GABAB receptors couple to G proteins Go, Go* and Gi1 but not to Gi2.

21 January 2018

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Adenosine receptor subtypes: characterization and therapeutic regulation

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Molecular cloning and characterization of a rat A1-adenosine receptor that is widely expressed in brain and spinal cord.

21 January 2018

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Immunohistochemical detection of A1 adenosine receptors in rat brain with emphasis on localization in the hippocampal formation, cerebral cortex, cerebellum, and basal ganglia

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Regional differences in the GTP-dependence of adenosine receptor binding in rat brain?

21 January 2018

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Autoradiographic evidence for multiple CNS binding sites for adenosine derivatives

21 January 2018

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Synaptic and extrasynaptic localization of adenosine binding sites in the rat hippocampus

21 January 2018

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Adenosine regulates via two different types of receptors, the accumulation of cyclic AMP in cultured brain cells

21 January 2018

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A1 adenosine receptors expressed in CHO-cells couple to adenylyl cyclase and to phospholipase C.

21 January 2018

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Stimulation of adenosine A1 receptors and bradykinin receptors, which act via different G proteins, synergistically raises inositol 1,4,5-trisphosphate and intracellular free calcium in DDT1 MF-2 smooth muscle cells

21 January 2018

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Adenosine inhibits L- and N-type calcium channels in pituitary melanotrophs. Evidence for the involvement of a G protein in calcium channel gating

21 January 2018

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Predominant role of A1 adenosine receptors in mediating adenosine induced vasodilatation of rat diaphragmatic arterioles: involvement of nitric oxide and the ATP‐dependent K+ channels

21 January 2018

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Reconstitution of Bovine A1 Adenosine Receptors and G Proteins in Phospholipid Vesicles: βγ-Subunit Composition Influences Guanine Nucleotide Exchange and Agonist Binding

21 January 2018

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[125I]Aminobenzyladenosine, a new radioligand with improved specific binding to adenosine receptors in heart

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

21 January 2018

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Pre- and postsynaptic GABAB receptors in the hippocampus have different pharmacological properties

21 January 2018

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Gsalpha-selective G protein antagonists

21 January 2018

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Two different forms of metarhodopsin II: Schiff base deprotonation precedes proton uptake and signaling state

21 January 2018

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Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine phosphorylation

21 January 2018

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Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors

21 January 2018

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G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons

21 January 2018

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The coupling of neurotransmitter receptors to ion channels in the brain

21 January 2018

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Binding of the G protein betagamma subunit to multiple regions of G protein-gated inward-rectifying K+ channels

21 January 2018

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Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by G beta gamma subunits and function as heteromultimers

21 January 2018

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Inhibition of an inwardly rectifying K+ channel by G-protein alpha-subunits.

21 January 2018

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Transducin-alpha C-terminal peptide binding site consists of C-D and E-F loops of rhodopsin

21 January 2018

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The effect of carboxyl-terminal mutagenesis of Gt alpha on rhodopsin and guanine nucleotide binding

21 January 2018

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Identification of a Gs-protein coupling domain to the beta-adrenoceptor using site-specific synthetic peptides. Carboxyl terminus of Gs alpha is involved in coupling to beta-adrenoceptors

21 January 2018

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Site of G protein binding to rhodopsin mapped with synthetic peptides from the alpha subunit

21 January 2018

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Adenosine A1 agonists and the Ca2+ channel agonist bay K 8644 produce a synergistic stimulation of the GTPase activity of Go in rat frontal cortical membranes.

21 January 2018

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21 January 2018

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Adenosine A1 receptors are located predominantly on axons in the rat hippocampal formation

21 January 2018

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Betagamma subunits of pertussis toxin-sensitive G proteins mediate A1 adenosine receptor agonist-induced activation of phospholipase C in collaboration with thyrotropin. A novel stimulatory mechanism through the cross-talk of two types of receptors

21 January 2018

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Regulation of L-Type Calcium Channels in GH4 Cells via A1 Adenosine Receptors

21 January 2018

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NMR structure of a receptor-bound G-protein peptide

21 January 2018

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Specific peptide probes for G-protein interaction with effectors

21 January 2018

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Whole cell recording from neurons in slices of reptilian and mammalian cerebral cortex

21 January 2018

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Formation of the meta II photointermediate is accompanied by conformational changes in the cytoplasmic surface of rhodopsin

21 January 2018

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Photoactivated conformational changes in rhodopsin: a time-resolved spin label study

21 January 2018

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Photoregeneration of bovine rhodopsin from its signaling state

21 January 2018

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Interaction of Transducin with Light-activated Rhodopsin Protects It from Proteolytic Digestion by Trypsin

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.24.14912

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9614095%20AND%20SRC:MED&resulttype=core&format=json

release_rp5n53o2orekzi3fq2bc4n3fie

12 November 2019

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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