XCL2

Hemokin (C motiv) ligand 2
Hemokin (C motiv) ligand 2
Identifikatori
Simbol	XCL2
Alt. simboli	SCYC2, SCM-1b
Entrez	6846
HUGO	10646
OMIM	604828
RefSeq	NM_003175
UniProt	Q9UBD3
Ostali podaci
Lokus	Hromozom 1 q24.2

XCL2, hemokin (C motiv) ligand 2, je mali citokin koji pripada XC hemokin familiji. On je u velikoj meri sličan XCL1 hemokinu.^[1] On je predominantno izražen u aktiviranim T ćelijama, ali se može takođe može naći u niskim koncentracijama u nestimulisanim ćelijama. XCL2 inducira hemotaksu ćelija koje izražavaju hemokin receptor XCR1.^[2] Njegov gen je lociran na hromozomu 1 kod ljudi.^[3]^[4]

Reference

^ Kennedy J, Kelner G, Kleyensteuber S, Schall T, Weiss M, Yssel H, Schneider P, Cocks B, Bacon K, Zlotnik A (1995). „Molecular cloning and functional characterization of human lymphotactin”. J Immunol. 155 (1): 203—9. PMID 7602097.
^ Yoshida T, Imai T, Kakizaki M, Nishimura M, Takagi S, Yoshie O (1998). „Identification of single C motif-1/lymphotactin receptor XCR1”. J Biol Chem. 273 (26): 16551—4. PMID 9632725. doi:10.1074/jbc.273.26.16551.
^ Yoshida T, Imai T, Takagi S, Nishimura M, Ishikawa I, Yaoi T, Yoshie O (1996). „Structure and expression of two highly related genes encoding SCM-1/human lymphotactin”. FEBS Lett. 395 (1): 82—8. PMID 8849694. doi:10.1016/0014-5793(96)01004-6.
^ Mire-Sluis, Anthony R.; Thorpe, Robin, ур. (1998). Cytokines (Handbook of Immunopharmacology). Boston: Academic Press. ISBN 0-12-498340-5.

Literatura

[1] Kennedy J, Kelner G, Kleyensteuber S, Schall T, Weiss M, Yssel H, Schneider P, Cocks B, Bacon K, Zlotnik A (1995). „Molecular cloning and functional characterization of human lymphotactin”. J Immunol. 155 (1): 203—9. PMID 7602097.

[2] Yoshida T, Imai T, Kakizaki M, Nishimura M, Takagi S, Yoshie O (1998). „Identification of single C motif-1/lymphotactin receptor XCR1”. J Biol Chem. 273 (26): 16551—4. PMID 9632725. doi:10.1074/jbc.273.26.16551.

[3] Yoshida T, Imai T, Takagi S, Nishimura M, Ishikawa I, Yaoi T, Yoshie O (1996). „Structure and expression of two highly related genes encoding SCM-1/human lymphotactin”. FEBS Lett. 395 (1): 82—8. PMID 8849694. doi:10.1016/0014-5793(96)01004-6.

[4] Mire-Sluis, Anthony R.; Thorpe, Robin, ур. (1998). Cytokines (Handbook of Immunopharmacology). Boston: Academic Press. ISBN 0-12-498340-5.

[1]