LPAR6
No campo da biologia molecular, o receptor de ácido lisofosfatídico, também conhecido como LPA6 e P2RY5, é uma proteína que pertence ao grupo dos receptores P2Y e que, em seres humanos, é codificada pelo gene LPAR6.[1][2][3]
Referências
- ↑ Adrian K, Bernhard MK, Breitinger HG, Ogilvie A (2000). «Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells». Biochim Biophys Acta. 1492 (1): 127–38. PMID 11004484
- ↑ Ralevic V, Burnstock G (1998). «Receptors for purines and pyrimidines». Pharmacol Rev. 50 (3): 413–92. PMID 9755289
- ↑ Yanagida K, Masago K, Nakanishi H, Kihara Y, Hamano F, Tajima Y, Taguchi R, Shimizu T, Ishii S (2009). «Identification and characterization of a novel lysophosphatidic acid receptor, p2y5/LPA6». J Biol Chem. 284 (26): 17731–41. PMC 2719412
. PMID 19386608. doi:10.1074/jbc.M808506200
Leitura de apoio
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- Herzog H, Darby K, Hort YJ, Shine J (1997). «Intron 17 of the human retinoblastoma susceptibility gene encodes an actively transcribed G protein-coupled receptor gene.». Genome Res. 6 (9): 858–61. PMID 8889552. doi:10.1101/gr.6.9.858
- Li Q, Schachter JB, Harden TK, Nicholas RA (1997). «The 6H1 orphan receptor, claimed to be the p2y5 receptor, does not mediate nucleotide-promoted second messenger responses.». Biochem. Biophys. Res. Commun. 236 (2): 455–60. PMID 9240460. doi:10.1006/bbrc.1997.6984
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K,; et al. (1997). «Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.». Gene. 200 (1-2): 149–56. PMID 9373149. doi:10.1016/S0378-1119(97)00411-3
- Strausberg RL, Feingold EA, Grouse LH,; et al. (2003). «Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.». Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMID 12477932. doi:10.1073/pnas.242603899
- Ota T, Suzuki Y, Nishikawa T,; et al. (2004). «Complete sequencing and characterization of 21,243 full-length human cDNAs.». Nat. Genet. 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285
- Dunham A, Matthews LH, Burton J,; et al. (2004). «The DNA sequence and analysis of human chromosome 13.». Nature. 428 (6982): 522–8. PMID 15057823. doi:10.1038/nature02379
- Gerhard DS, Wagner L, Feingold EA,; et al. (2004). «The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).». Genome Res. 14 (10B): 2121–7. PMID 15489334. doi:10.1101/gr.2596504
- Ihara H, Hirukawa K, Goto S, Togari A (2005). «ATP-stimulated interleukin-6 synthesis through P2Y receptors on human osteoblasts.». Biochem. Biophys. Res. Commun. 326 (2): 329–34. PMID 15582581. doi:10.1016/j.bbrc.2004.11.037
