Talk:Albendazole

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What is the dose of albendazole to be taken for a patient having Hook Worm ++?

−The FDA only allows this drug to be indicated for the treatment of Pork Tapeworm, and Dog Tapeworm. Doctors may use it to treat other infestations as literature (JAMA) is presented Sammorxman 15:51, 13 October 2006 (UTC)Sam M. Pharmacist[reply]

You have to take one tablet when you want to treat against hookworm. The tablet is 400mg in the case of Zentel. 121.247.54.127 07:57, 5 September 2007 (UTC)[reply]

Is it safe for us to be providing dosages on wikipedia? I really don't think it's a good idea. —Preceding unsigned comment added by RamziE (talk • contribs) 05:55, 5 December 2009 (UTC)[reply]

Dosage information should not be hidden, but a credible source should be cited instead of providing this information "verbatim" - which might, unfortunately, prove difficult as a suitable reference providing the same summary may not exist and/or is likely not freely available. Wikipedia is a community driven project and as such community "policed". Accurate as well as inaccurate information may be added by anyone. In today's day and age, cross references to dosage information are readily available and can be easily verified. If you personally feel insecure about providing dosage amounts, just don't do it.

[[[Special:Contributions/66.46.103.18|66.46.103.18]] (talk) 20:39, 5 January 2011 (UTC)][reply]

In this website: http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm

says that albendazole has been approved since 1996, contrary to what it states on this article. --Felipebm (talk) 12:26, 25 January 2008 (UTC)[reply]

I have removed 86.185.210.221 (talk) 15:11, 11 May 2014 (UTC)[reply]

This article was automatically assessed because at least one WikiProject had rated the article as stub, and the rating on other projects was brought up to Stub class. BetacommandBot 07:51, 10 November 2007 (UTC)[reply]

see http://www.wjgnet.com/1007-9327/10/1215.pdf —Preceding unsigned comment added by 189.7.84.149 (talk) 06:48, 30 May 2009 (UTC)[reply]

How likely is this ? The symptoms of this drug sound worse than the infection. Mebendazole seems to have fewer and less severe symptoms. —Preceding unsigned comment added by 219.133.146.132 (talk) 15:23, 17 June 2010 (UTC)[reply]

such symptoms are unlikely in 'casual' dosages, yet article is indeed deficient in specifics at which dosages which side effects do occur, and which ones are related to drug itself - some of these overlap with symptoms of being exposed to toxins of dying worms.

this section surely needs more attention, perhaps it's even worth extending article with list of symptoms comig from worms toxins alone, both short term and long term for reference.

also, there is very little data in article about veterinary use. at least some general info with references would be usefull.

83.18.229.186 (talk) 22:50, 26 October 2011 (UTC)[reply]

I check pages listed in Category:Pages with incorrect ref formatting to try to fix reference errors. One of the things I do is look for content for orphaned references in wikilinked articles. I have found content for some of Albendazole's orphans, the problem is that I found more than one version. I can't determine which (if any) is correct for this article, so I am asking for a sentient editor to look it over and copy the correct ref content into this article.

Reference named "AHFS":

• From Ibandronic acid: "boniva". The American Society of Health-System Pharmacists. Retrieved 3 April 2011.
• From Carbamazepine: "Carbamazepine". The American Society of Health-System Pharmacists. Retrieved 3 April 2011.
• From Amoxicillin: "Amoxicillin". The American Society of Health-System Pharmacists. Retrieved 3 April 2011.
• From Salbutamol: "Albuterol". The American Society of Health-System Pharmacists. Retrieved 3 April 2011.

I apologize if any of the above are effectively identical; I am just a simple computer program, so I can't determine whether minor differences are significant or not. AnomieBOT⚡ 12:28, 31 December 2014 (UTC)[reply]

Hello @Artoria2e5: I have checked this edit and the text is inaccurate. Albendazole is not known to have an effect on Drosophila but instead on Wolbachia. The title of Serbus reflects that. I am also unable to find any reviews that endorse Serbus entirely. Almost all (doi:10.1099/vir.0.057422-0, doi:10.1016/j.bioorg.2014.03.007, doi:10.1111/febs.13781 doi:10.1002/wdev.339) simply point to it as an interesting result or even merely as a good methodology, with only doi:10.3390/tropicalmed4030108 even describing the results as so much as "putative". How should we change the text? Invasive Spices (talk) 14 December 2021 (UTC)

Invasive Spices, I believe the linked edit about Drosophila already quite cleary states that it does *not* target the insect directly. For the lack of secondary references... I believe we should put a {{primary source inline}} up for now. I would love to phrase it so it does not seem medically relevant, but only interesting from a structual biology perspective with regard to tubulin variation. --Artoria2e5 🌉 13:40, 19 December 2021 (UTC)[reply]

The text is Drosophila have many of the same mutations, meaning the drug does not affect fruit flies. Drosophila and Wolbachia are not the same thing. One is the host and the other the symbiont. Drosophila does not have the same mutations as the Platyhelminthes in the preceding ref (the tablet info link). What Serbus does say is that Drosophila microtubules are unaffected by albendazole - not due to mutation, but just normally. They also found that albendazole did suppress Wolbachia anyhow. They put this all together to indicate that albendazole acts against Wolbachia but not Drosophila. Secondary I agree that this is not medically relevant. I did not bring this up to deal with MEDRS, which I agree already does not apply here. What I mean is that after 9 years there have been no flattering citations in reviews which tells me this is not taken seriously. Instead perhaps we should substitute doi:10.1128/microbiolspec.BAI-0018-2019 which cites doi:10.1073/pnas.1710845114? Invasive Spices (talk) 21 December 2021 (UTC)

@Artoria2e5: I have made the edit here. I simply removed Serbus because I am unable to find any citation of its results. It is unusually widely cited for its photography or its methodology or other reasons – but for whatever reason never as a valid result. I have not searched extensively enough for a real replacement to be certain – there may be albendazole + Drosophila + Wolbachia research that I have not found that would be a good replacement – but I have stopped searching. If you have something else I am in favor of adding it also. Invasive Spices (talk) 19 February 2022 (UTC)

How long will it remain effective in storage with good conditions? 2603:6081:8F01:3171:354B:BD6B:23CF:FB32 (talk) 11:29, 19 March 2023 (UTC)[reply]

Sorry, Talk pages are not for random discussion about article topics. They are there to discuss improvements to the article. See Wikipedia:Talk page guidelines. — kashmīrī ^TALK 14:40, 19 March 2023 (UTC)[reply]