Talk:ATPase
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This article was the subject of a Wiki Education Foundation-supported course assignment, between 11 January 2022 and 10 May 2022. Further details are available on the course page. Student editor(s): Rmcconne (article contribs). Peer reviewers: Ecaldero, Grace.volk7.
Error?
editIs this an error?
for example, 3 Na+ ions inward and 2 K+ ions outward per ATP hydrolyzed, for the Na+/K+ exchanger.
seeNaKATPase Function section
- You are absolutely right, I changed this. -postglock 14:25, 6 April 2006 (UTC)
ATPase vs ATP Synthase
editAlso, does anyone know if ATPase is strictly an enzyme that dephosphorylises (is that a word?) ATP? My bio lecturer uses that same word for ATP synthase in mitochondria. Similarly, does anyone know if the -ase suffix suggests enzymes that that break down the root of the name? I suspect not, ala, RNA polymerase.... -postglock 14:25, 6 April 2006 (UTC)
- Yes dephosphorylises is a word, second no. F- ATPases work like V-ATPases but in reverse allowing H+ to flow with the gradient and makes ATP with the energy dived. The worked of the Cell by Becker, Kleinsmith and Hardin has a good chapter on ATPases. I’ll up date this article from the information with in it soon if there are no objections. -jasoninkid 16 April 2006
Thanks for the response, and certainly update the article with the information, any positive additions are appreciated! I'm still don't understand this completely though, I mean, if ATP synthase works in reverse, and also has the capability to work like an ATPase, then could it be (structurally) called an ATPase? -postglock 01:14, 17 April 2006 (UTC)
- Right now both articles describe the same proteins. Perhaps merging is needed.Biophys (talk) 03:54, 25 December 2007 (UTC)
Quibbles
editDephosphorylises is not a word I'm familiar with; instead, I've always heard "dephosphorylates." I could just be ignorant of terminology used in other countries, but thought I'd mention it.
Next, it would be nice if the section on ATPases that dephosphorylate would be expanded, since, even though the definition says that ATPases do this, synthases (which I've also heard called ATPases) make the bulk of examples. I don't know the classifications, as I'm still an undergrad student in Molecular Biology, but to begin, RecA and homologs in recombination could add to the section.
It might be useful to mention something about similar mechanisms that activate other molecules, like cAMP-dependent G-protein Linked Receptors. This could be a "similar mechanisms" section or "not to be confused with." RegiG (talk) 19:58, 25 June 2008 (UTC)
The font in the ADP image doesn't scale. --Nasorenga (talk) 20:26, 2 November 2008 (UTC)
Assessment comment
editThe comment(s) below were originally left at Talk:ATPase/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.
| Rated "high" as high school/SAT biology content. The article would benefit from figures and expansion beyond transmembrane ATPases (e.g. adding other families such as AAA+ ATPases etc.) - tameeria 23:02, 18 February 2007 (UTC) |
Last edited at 23:02, 18 February 2007 (UTC). Substituted at 06:27, 29 April 2016 (UTC)
What is the simplest possible ATPase?
editWhat are the most primitive, the most ancient, the simplest possible ATPases? 67.198.37.16 (talk) 19:31, 3 November 2018 (UTC)
EC 3.6.1.3 references to a deleted article
editUnder https://iubmb.qmul.ac.uk/enzyme/EC3/6/1/3.html one finds the error message "Deleted entry: adenosinetriphosphatase. Enzymes previously listed under this number are now listed separately under EC 5.6 and EC 7." Also according to https://enzyme.expasy.org/cgi-bin/enzyme/enzyme-search-ec this enzyme has been removed. Please correct the EC number to match the updated number. — Preceding unsigned comment added by Knackigkurz (talk • contribs) 15:16, 18 January 2022 (UTC)