Royal Infirmary may refer to a number of hospitals in the United Kingdom:
- England
- Blackburn Royal Infirmary
- Bradford Royal Infirmary
- Bolton Royal Infirmary
- Bristol Royal Infirmary
- Chester Royal Infirmary
- Derbyshire Royal Infirmary
- Doncaster Royal Infirmary
- Gloucestershire Royal Infirmary
- Royal Halifax Infirmary
- Huddersfield Royal Infirmary
- Hull Royal Infirmary
- Lancaster Royal Infirmary
- Leicester Royal Infirmary
- Liverpool Royal Infirmary
- Royal Infirmary for Children and Women, Lambeth, London
- Manchester Royal Infirmary
- Royal Victoria Infirmary, Newcastle
- North Staffordshire Royal Infirmary
- Preston Royal Infirmary
- Salford Royal Infirmary
- Sheffield Royal Infirmary
- Scotland
- Wales