File:Selective-anticancer-activity-of-a-hexapeptide-with-sequence-homology-to-a-non-kinase-domain-of-1476-4598-10-72-S1.ogv

English: Time Lapse Photomicrographic Video of H460 human non-small lung cancer cells exposed in-vitro to 200 μM THR53. H460 cells were grown in the presence of 200 μM THR53 in Ham's F12 medium + 10% FCS. Micrographic video frames at ×40 magnification were taken at 20 minute intervals and are shown at 7 frames per second. In contrast to control H460 cells, grown in the same medium in the absence of THR53 (see below), although undergoing repeated cell divisions, treated H460 cells show progressive cell death throughout succesive divisions, typified by cellular swelling, vacuolation and disintegration. There is no morphological evidence of apoptosis.