"Take turns playing as a team of humans and mutants in a moshpit of modes. Mutants possess a series of unique abilities that can stun, disorientate, and eliminate the enemy humans. Switch sides at half time."
— Playlist Description
Mutation is a limited-time multiplayer game mode featured in Call of Duty: Modern Warfare III. It was added on June 26th, 2024 as part of the Season Four Reloaded update and remained in the game until the launch of Season Five on July 24th, 2024. Mutation returned on September 18th, 2024 as part of the Season Six update.
The mode works as a playlist featuring the Team Deathmatch, Kill Confirmed, Domination and Hardpoint modes. One team is playing as Mutants with unique special abilities while the other team is playing as Humans operators with their main loadout. Each matche plays in two rounds with every player switching teams for the second round.
Mutants Abilities[]
Mutants
Abilities
Mutated Leaper
Charged Leap
Leap at the enemy with a ground breaking impact.
Snapshot Grenade
Toss a Snapshot Grenade to reveal enemies for your team.
Mutant Rage
Fast movement, increased melee damage, ability to detect enemies around corners.
Camouflaged Sneaker
Scramble
Leap at the enemy with a lethal shockwave impact.
EMP Throw
Throw a lethal energy projectile at the enemy, than can also stun and slow.
Cloak
Become partially invisible for a brief period of time.
Contaminated Sludger
Explode
Explode with a large radius of mutant sludge, does not count as a death.
Smoke Grenade
Toss a Smoke Grande to shroud fellow mutants from the enemy.
Acid Blast
Eject a strong acid blast that deals close range damage, and leaves pools of acid that damage and slow the enemy.
Radioactive Beast
Charge
Stampede toward the enemy for an Earth shattering impact.
Howl
Shellshock nearby enemies with a deafening howl, temporarily buff teammate health and move speed.
Seismic Recon
Reveal nearby enemies on the minimap for your team.
Modifiers[]
Several Modifiers are also available for the Mutant side. The Modifiers were earned during the Altered Strain event.
Name
Icon
Description
First Strike
Rapid cooldown on first Ability used after respawn
Flop Shot
Diving from elevated surface produces a small explosion
Repocket
Kills with Abilities have a chance to replenish your tactical ability