pentostatin (Q425470)

pentostatin (English)

(8S)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-8-ol

19 October 2016

stereoisomer of

1 reference

based on heuristic

inferred from InChI

chemical formula

C₁₁H₁₆N₄O₄

1 reference

pentostatin (English)

19 November 2016

canonical SMILES

C1C(C(OC1N2C=NC3=C2NC=NCC3O)CO)O

1 reference

pentostatin (English)

19 November 2016

isomeric SMILES

C1[C@@H]([C@H](O[C@H]1N2C=NC3=C2NC=NC[C@H]3O)CO)O

1 reference

pentostatin (English)

World Health Organisation international non-proprietary name

19 November 2016

pentostatin (English)

1 reference

Pentostatin (English)

Streptomyces antibioticus

19 January 2016

found in taxon

2 references

Improved production of pentostatin and identification of fermentation cometabolites

ISOLATION AND PROPERTIES OF A VIDARABINE DEAMINASE INHIBITOR, CO-VIDARABINE

medical condition treated

1 reference

chronic lymphocytic leukemia

13 December 2016

1 reference

Drug Indications Extracted from FAERS

significant drug interaction

2 October 2018

fludarabine

pulmonary toxicity

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-cyclophosphamide

bone marrow failure

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fludarabine

bone marrow failure

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-cyclophosphamide

embolism

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-cyclophosphamide

cardiotoxicity

1 reference

A reference set of clinically relevant adverse drug-drug interactions

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4805

https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802

17 August 2016

legal status (medicine)

boxed warning

1 reference

reference URL

imported from Wikimedia project

FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (English)

pregnancy category

US pregnancy category D

1 reference

1 reference

5 March 2018

DNA polymerase inhibitors

1 reference

5 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

D015649

adenosine deaminase inhibitors

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

D015649

15 March 2018

developmental toxicant

start time

1 September 1996

1 reference

California Proposition 65 list of chemicals

https://oehha.ca.gov/chemicals/pentostatin

18 March 2020

reference URL

Commons category

Pentostatin

0 references

Identifiers

InChI

InChI=1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1

1 reference

pentostatin (English)

19 November 2016

1 reference

pentostatin (English)

19 November 2016

2 references

pentostatin (English)

19 November 2016

https://commonchemistry.cas.org/detail?cas_rn=53910-25-1

8 April 2021

1 reference

DCF (English)

19 November 2016

2 references

pentostatin (English)

19 November 2016

ChEBI ID

27834

mapping relation type

exact match

1 reference

International Chemical Identifier

InChI

InChI=1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1

1 reference

PENTOSTATIN (English)

19 November 2016

2 references

inferred from InChIKey

Cambridge Structural Database

1 reference

1 reference

10 January 2023

1 reference

Cambridge Structural Database

10 January 2023

1 reference

Hazardous Substances Data Bank

28 October 2019

PENTOSTATIN (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.164.991

27 December 2018

ECHA Substance Infocard ID

(8R)-3-(2-Deoxy-b-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol (English)

quotation

CAS no.: 53910-25-1 (English)

100.164.991

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.164.991

27 December 2018

(8R)-3-(2-Deoxy-b-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol (English)

quotation

CAS no.: 53910-25-1 (English)

1 reference

Guide to Pharmacology Ligand ID

Pentostatin (English)

publication date

17 November 2015

4805

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4805

D03.383.742.680.350.200.700

pentostatin (English)

19 November 2016

Pentostatin

0 references

MeSH concept ID

M0023987

0 references

MeSH tree code

0 references

D13.570.230.677

0 references

D13.570.685.350.200.700

0 references

RxNorm ID

8011

1 reference

pentostatin (English)

19 November 2016

DrugBank ID

DB00552

1 reference

Human Metabolome Database ID

HMDB0014692

2 references

based on heuristic

inferred from InChIKey

2 references

pentostatin (English)

19 November 2016

Natural Product Atlas ID

NPA032760

2 references

based on heuristic

inferred from InChIKey

MedlinePlus drug identifier

a692004

0 references

PatientsLikeMe treatment ID

0 references

1 reference

pentostatin (English)

19 November 2016

0 references

1 reference

1 reference

California Proposition 65 list of chemicals

Pentostatin (English)

19 January 2016

0 references

1 reference

https://oehha.ca.gov/chemicals/pentostatin

7 January 2020

reference URL

0 references

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

1A4L (English)

19 October 2016

1 reference

2PGR (English)

19 October 2016

1 reference

pentostatin (English)