CEA cell adhesion molecule 6 (Q21155687)

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mammalian protein found in Homo sapiens

carcinoembryonic antigen-related cell adhesion molecule 6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
carcinoembryonic antigen related cell adhesion molecule 6
Non-specific crossreacting antigen
normal cross-reacting antigen
CEACAM6
Cluster of Differentiation 66c
CEACAM6 protein, human

Language	Label	Description	Also known as
English	CEA cell adhesion molecule 6	mammalian protein found in Homo sapiens	carcinoembryonic antigen-related cell adhesion molecule 6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) carcinoembryonic antigen related cell adhesion molecule 6 Non-specific crossreacting antigen normal cross-reacting antigen CEACAM6 Cluster of Differentiation 66c CEACAM6 protein, human

Statements

1 reference

13 November 2019

UniProt protein ID

Immunoglobulin-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P40199

Immunoglobulin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P40199

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Immunoglobulin subtype, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin V-set domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin subtype 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

immunoglobulin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method or standard

1 reference

8 April 2019

A secreted protein microarray platform for extracellular protein interaction discovery

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

identical protein binding

determination method or standard

1 reference

24 April 2018

Diverse oligomeric states of CEACAM IgV domains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40199&geneProductId=UniProtKB:P40199

determination method or standard

protein heterodimerization activity

determination method or standard

1 reference

8 April 2019

Diverse oligomeric states of CEACAM IgV domains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

integral component of plasma membrane

determination method or standard

1 reference

24 April 2018

Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40199&geneProductId=UniProtKB:P40199

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

extracellular space

determination method or standard

1 reference

8 April 2019

Human neutrophils secrete bioactive paucimannosidic proteins from azurophilic granules into pathogen-infected sputum

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

azurophil granule membrane

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

determination method or standard

4 references

5 June 2018

Preparation and characterization of two human carcinoembryonic antigen family proteins of neutrophils, CD66b and c, in silkworm larvae

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40199&geneProductId=UniProtKB:P40199

determination method or standard

5 June 2018

Expression of complementary DNA and genomic clones for carcinoembryonic antigen and nonspecific cross-reacting antigen in Chinese hamster ovary and mouse fibroblast cells and characterization of the membrane-expressed products

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40199&geneProductId=UniProtKB:P40199

determination method or standard

5 June 2018

Inhibition of adhesion, invasion, and metastasis by antibodies targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen).

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40199&geneProductId=UniProtKB:P40199

determination method or standard

5 June 2018

Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40199&geneProductId=UniProtKB:P40199

determination method or standard

apical plasma membrane

determination method or standard

1 reference

5 June 2018

Four carcinoembryonic antigen subfamily members, CEA, NCA, BGP and CGM2, selectively expressed in the normal human colonic epithelium, are integral components of the fuzzy coat

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40199&geneProductId=UniProtKB:P40199

determination method or standard

anchored component of membrane

determination method or standard

determination method or standard

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

8 April 2019

Preparation and characterization of two human carcinoembryonic antigen family proteins of neutrophils, CD66b and c, in silkworm larvae

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

8 April 2019

Expression of complementary DNA and genomic clones for carcinoembryonic antigen and nonspecific cross-reacting antigen in Chinese hamster ovary and mouse fibroblast cells and characterization of the membrane-expressed products

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

8 April 2019

Inhibition of adhesion, invasion, and metastasis by antibodies targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen).

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

8 April 2019

Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

apical plasma membrane

determination method or standard

biological process

cell-cell signaling

determination method or standard

1 reference

24 April 2018

Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40199&geneProductId=UniProtKB:P40199

determination method or standard

leukocyte migration

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

positive regulation of cell population proliferation

determination method or standard

1 reference

8 April 2019

MicroRNA-29a suppresses the growth, migration, and invasion of lung adenocarcinoma cells by targeting carcinoembryonic antigen-related cell adhesion molecule 6

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

positive regulation of cell migration

determination method or standard

2 references

neutrophil degranulation

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

homophilic cell adhesion via plasma membrane adhesion molecules

determination method or standard

2 references

8 April 2019

Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

8 April 2019

Identification and comparison of residues critical for cell-adhesion activities of two neutrophil CD66 antigens, CEACAM6 and CEACAM8

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

determination method or standard

3 references

8 April 2019

Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

8 April 2019

Identification and comparison of residues critical for cell-adhesion activities of two neutrophil CD66 antigens, CEACAM6 and CEACAM8

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

8 April 2019

Preparation and characterization of two human carcinoembryonic antigen family proteins of neutrophils, CD66b and c, in silkworm larvae

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

signal transduction

determination method or standard

2 references

24 April 2018

Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40199&geneProductId=UniProtKB:P40199

determination method or standard

24 April 2018

CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P40199&geneProductId=UniProtKB:P40199

determination method or standard

positive regulation of heterotypic cell-cell adhesion

determination method or standard

1 reference

8 April 2019

Inhibition of adhesion, invasion, and metastasis by antibodies targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen).

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

positive regulation of endothelial cell-matrix adhesion via fibronectin

determination method or standard

1 reference

8 April 2019

Inhibition of adhesion, invasion, and metastasis by antibodies targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen).

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

negative regulation of anoikis

determination method or standard

signal transduction

determination method or standard

1 reference

8 April 2019

CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

apoptotic process

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40199

determination method or standard

Identifiers

MeSH descriptor ID

subject named as

CEACAM6 protein, human

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000199764

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000199764

ENSP00000469752

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000469752

0 references

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(5 entries)

dewiki CD66c
enwiki CEACAM6
ruwiki CEACAM6
ttwiki CEACAM6
ukwiki CEACAM6

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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