rifabutin (Q1135705)

17 November 2015

Rifabutin structure.svg
512 × 460; 13 KB

0 references

mass

846.442 dalton

1 reference

RIFABUTIN (English)

17 November 2016

C₄₆H₆₂N₄O₁₁

1 reference

RIFABUTIN (English)

17 November 2016

CC1C=CC=C(C(=O)NC2=C3C(=NC4(N3)CCN(CC4)CC(C)C)C5=C6C(=C(C(=C5C2=O)O)C)OC(C6=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C

1 reference

RIFABUTIN (English)

17 November 2016

C[C@H]1/C=C/C=C(\C(=O)NC2=C3C(=NC4(N3)CCN(CC4)CC(C)C)C5=C6C(=C(C(=C5C2=O)O)C)O[C@@](C6=O)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)/C

1 reference

https://www.whocc.no/atc_ddd_index/?code=J04AB04

RIFABUTIN (English)

17 November 2016

0.15 gram

route of administration

oral administration

1 reference

reference URL

1 reference

14 February 2018

World Health Organisation international non-proprietary name

rifabutin (English)

1 reference

Ansamycin antibiotics as free radical scavengers isolated from Streptomyces by using the bactericidal action of the hydroxyl radical

Rifabutin (English)

19 January 2016

1 reference

medical condition treated

pulmonary tuberculosis

1 reference

English

Mycobacterium avium-intracellulare infection

13 December 2016

2 references

English

13 December 2016

Drug Indications Extracted from FAERS

significant drug interaction

2 October 2018

clarithromycin

uveitis

1 reference

A reference set of clinically relevant adverse drug-drug interactions

uveitis

1 reference

A reference set of clinically relevant adverse drug-drug interactions

visual impairment

1 reference

A reference set of clinically relevant adverse drug-drug interactions

blindness

1 reference

A reference set of clinically relevant adverse drug-drug interactions

photophobia

1 reference

A reference set of clinically relevant adverse drug-drug interactions

eye pain

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cobicistat

1 reference

hypothetically

A reference set of clinically relevant adverse drug-drug interactions

pregnancy category

Australian pregnancy category C

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category B

1 reference

imported from Wikimedia project

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category D

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Rifabutin

10 June 2018

1 reference

https://www.pfizer.com/products/product-list

subject has role

DNA polymerase inhibitors

1 reference

5 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

D017828

antitubercular antibiotics

15 March 2018

1 reference

‎WHO Aware Classification

Medical Subject Headings

15 March 2018

0 references

1 reference

watch

1 reference

2023 ‎AWaRe classification‎

Commons category

Rifabutin

0 references

Identifiers

InChI

InChI=1S/C46H62N4O11/c1-22(2)21-50-18-16-46(17-19-50)48-34-31-32-39(54)28(8)42-33(31)43(56)45(10,61-42)59-20-15-30(58-11)25(5)41(60-29(9)51)27(7)38(53)26(6)37(52)23(3)13-12-14-24(4)44(57)47-36(40(32)55)35(34)49-46/h12-15,20,22-23,25-27,30,37-38,41,49,52-54H,16-19,21H2,1-11H3,(H,47,57)/b13-12+,20-15+,24-14-/t23-,25+,26+,27+,30-,37-,38+,41+,45-/m0/s1

1 reference

ATEBXHFBFRCZMA-VXTBVIBXSA-N

RIFABUTIN (English)

17 November 2016

2 references

RIFABUTIN (English)

17 November 2016

ChEBI release 2020-09-01

CAS Registry Number

72559-06-9

1 reference

Global Substance Registration System

UNII

1W306TDA6S

rifabutin (English)

17 November 2016

1 reference

RIFABUTIN (English)

19 October 2016

1 reference

RIFABUTIN (English)

17 November 2016

mapping relation type

3 references

matched by identifier from

RIFABUTIN (English)

17 November 2016

ChEBI release 2019-10-02

International Chemical Identifier

1 reference

matched by identifier from

RIFABUTIN (English)

17 November 2016

2 references

inferred from InChIKey

InChIKey

ATEBXHFBFRCZMA-VXTBVIBXSA-N

HSDB ID

3577

1 reference

Hazardous Substances Data Bank

28 October 2019

RIFABUTIN (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

matched by identifier from

InChIKey

ATEBXHFBFRCZMA-VXTBVIBXSA-N

DSSTOX compound identifier

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.133.627

ECHA Substance Infocard ID

27 December 2018

title

Spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2',3':7,8]naphth[1,2-d]imidazole-2,4'-piperidine]-5,10,26(3H,9H)-trione, 16-(acetyloxy)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-, (9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)- (English)

quotation

CAS no.: 72559-06-9 (English)

100.133.627

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.133.627