Lactacystin (Q6468907)

C15H24N2O7S (English)

L-Cysteine, N-acetyl-, 3-hydroxy-2-(1-hydroxy-2-methylpropyl)-4-methyl-5-oxo-2-pyrrolidinecarboxylate (ester), [2R-[2alpha,2(S*),3alpha,4.]]-

21 September 2016

stereoisomer of

2 references

inferred from InChIKey

inferred from InChI

chemical formula

C₁₅H₂₄N₂O₇S

1 reference

C15H24N2O7S (English)

21 September 2016

canonical SMILES

CC1C(C(NC1=O)(C(C(C)C)O)C(=O)SCC(C(=O)O)NC(=O)C)O

1 reference

C15H24N2O7S (English)

Streptomyces lactacystinicus

21 September 2016

isomeric SMILES

C[C@@H]1[C@@H]([C@](NC1=O)([C@H](C(C)C)O)C(=O)SC[C@@H](C(=O)O)NC(=O)C)O

0 references

found in taxon

2 references

Corrigendum: Streptomyces lactacystinicus sp. nov. and Streptomyces cyslabdanicus sp. nov., producing lactacystin and cyslabdan, respectively

The 20S proteasome of Streptomyces coelicolor.

Streptomyces

3 references

Biosynthesis of lactacystin. Origin of the carbons and stereospecific NMR assignment of the two diastereotopic methyl groups

Biosynthesis of Lactacystin

Structure of lactacystin, a new microbial metabolite which induces differentiation of neuroblastoma cells

Metulocladosporiella

1 reference

Isolation, structure, and biological activities of Fellutamides C and D from an undescribed Metulocladosporiella (Chaetothyriales) using the genome-wide Candida albicans fitness test.

subject has role

antibiotic

1 reference

Medical Subject Headings

MeSH descriptor ID

C067713

cysteine proteinase inhibitors

15 March 2018

1 reference

InChI=1S/C15H24N2O7S/c1-6(2)10(19)15(11(20)7(3)12(21)17-15)14(24)25-5-9(13(22)23)16-8(4)18/h6-7,9-11,19-20H,5H2,1-4H3,(H,16,18)(H,17,21)(H,22,23)/t7-,9+,10+,11+,15-/m1/s1

Medical Subject Headings

15 March 2018

Lactacystin

0 references

Identifiers

InChI

0 references

1 reference

ChEBI release 2020-09-01

CAS Registry Number

133343-34-7

1 reference

https://commonchemistry.cas.org/detail?cas_rn=133343-34-7

9 April 2021

1 reference

N-Acetyl-S-({(3S,4R)-3-hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxo-2-pyrrolidinyl}carbonyl)-L-cysteine (English)

21 September 2016

PubChem CID

6610292

1 reference

imported from Wikimedia project

ChEBI ID

52722

mapping relation type

exact match

2 references

English Wikipedia

International Chemical Identifier

InChI

InChI=1S/C15H24N2O7S/c1-6(2)10(19)15(11(20)7(3)12(21)17-15)14(24)25-5-9(13(22)23)16-8(4)18/h6-7,9-11,19-20H,5H2,1-4H3,(H,16,18)(H,17,21)(H,22,23)/t7-,9+,10+,11+,15-/m1/s1

SureChEMBL ID

SCHEMBL18254

2 references

inferred from InChIKey

1 reference

1 reference

DSSTOX compound identifier

DTXCID001326766

0 references

Nikkaji ID

J363.724G

1 reference

imported from Wikimedia project

Japanese Wikipedia

Wikimedia import URL

https://ja.wikipedia.org/w/index.php?title=ラクタシスチン&oldid=68360185

MeSH descriptor ID

C067713

1 reference

Medical Subject Headings

MeSH descriptor ID

C067713

14 March 2018

Natural Product Atlas ID

NPA020681

2 references

inferred from InChIKey

https://docs.openalex.org/download-snapshot/snapshot-data-format

0 references

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

UMLS CUI

C0125179

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023