GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand (Q47897710)

6 February 2018

http://europepmc.org/abstract/MED/28846099

title

GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand (English)

1 reference

6 February 2018

http://europepmc.org/abstract/MED/28846099

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1 reference

GDNF family receptor alpha like

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Growth differentiation factor 15

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positive regulation of protein kinase B signaling

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GDNF family receptor alpha like

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Ret proto-oncogene

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1 reference

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10 June 2020

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10 June 2020

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10 June 2020

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10 June 2020

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10 June 2020

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10 June 2020

Sebastian Beck Jørgensen

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10 June 2020

Linda Yang

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10 June 2020

Zhe Sun

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10 June 2020

Dennis Madsen

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10 June 2020

Søren B Padkjær

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10 June 2020

Xiaoai Wu

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10 June 2020

Tao Huang

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10 June 2020

Karin Hultman

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10 June 2020

Sarah J Paulsen

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10 June 2020

Jishu Wang

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10 June 2020

Jane Boesen Frantzen

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10 June 2020

Per Nørgaard

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10 June 2020

Jacob Fuglsbjerg Jeppesen

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10 June 2020

Zhiru Yang

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10 June 2020

Anna Secher

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10 June 2020

Linu Mary John

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10 June 2020

Bing Shan

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10 June 2020

Zhenhua He

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10 June 2020

Jing Su

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10 June 2020

Kristian T Hansen

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10 June 2020

Wei Yang

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10 June 2020

language of work or name

English

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publication date

28 August 2017

1 reference

6 February 2018

http://europepmc.org/abstract/MED/28846099

published in

Nature Medicine

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10 June 2020

volume

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10 June 2020

issue

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10 June 2020

page(s)

1158-1166

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Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1.

10 June 2020

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Macrophage inhibitory cytokine 1 (MIC-1/GDF15) decreases food intake, body weight and improves glucose tolerance in mice on normal & obesogenic diets

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Serum Levels of Human MIC-1/GDF15 Vary in a Diurnal Pattern, Do Not Display a Profile Suggestive of a Satiety Factor and Are Related to BMI.

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The anorectic actions of the TGFβ cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract

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MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily

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21 January 2018

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Identification, expression and functional characterization of the GRAL gene

21 January 2018

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21 January 2018

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The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation

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21 January 2018

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Genetic deletion of growth differentiation factor 15 augments renal damage in both type 1 and type 2 models of diabetes

21 January 2018

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The transforming growth factor-beta superfamily member growth-differentiation factor-15 protects the heart from ischemia/reperfusion injury

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GDF15 contributes to radiation-induced senescence through the ROS-mediated p16 pathway in human endothelial cells

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21 January 2018

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Progressive postnatal motoneuron loss in mice lacking GDF-15.

21 January 2018

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TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator

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Glial cell line-derived neurotrophic factor protects against high-fat diet-induced obesity.

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NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism

21 January 2018

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1 reference

PubMed

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