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Observational Study
. 2020 Oct 23;155(8):340-343.
doi: 10.1016/j.medcli.2020.06.020. Epub 2020 Jul 9.

Infection and thrombosis associated with COVID-19: Possible role of the ABO blood group

[Article in English, Spanish]
Saioa Zalba Marcos  1 , María Luisa Antelo  2 , Arkaitz Galbete  3 , Maialen Etayo  1 , Eva Ongay  4 , José Antonio García-Erce  5
Affiliations
Observational Study

Infection and thrombosis associated with COVID-19: Possible role of the ABO blood group

[Article in English, Spanish]
Saioa Zalba Marcos et al. Med Clin (Barc). .

Abstract

Background: SARS-CoV-2 infection is clinically very heterogeneous, varying from asymptomatic to severe clinical conditions with a fatal outcome. Some studies suggests that the ABO blood group could be a biological marker of susceptibility for the development of the disease.

Patients and methods: We collected data from patients admitted with COVID-19 infection who had ABO blood group recorded, and analyzed the incidence by groups, compared with the global population in Navarre, as well as their main complications and evolution.

Results: Group O was proportionally less represented in the hospitalized patients with respect to the global population, although the difference was not statistically significant. Group B had significantly higher rates of thrombotic complications and required more admissions in intensive care units.

Conclusion: The study suggests a lower susceptibility to infection in group O and a higher risk of complications in group B. Studies with a larger sample size are required in order to obtain significant results.

Keywords: Blood groups ABO; COVID-19; Coronavirus; Factor de von Willebrand; Factores de riesgo; Grupos sanguíneos ABO; Risk factors; SARS-CoV-2; Von Willebrand factor.

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