Lead poisoning: historical aspects of a paradigmatic "occupational and environmental disease"
- PMID: 22953225
- PMCID: PMC3430923
- DOI: 10.5491/SHAW.2012.3.1.11
Lead poisoning: historical aspects of a paradigmatic "occupational and environmental disease"
Abstract
Lead poisoning is one of the earliest identified and most known occupational disease. Its acute effects have been recognized from antiquity when this condition principally afflicted manual workers and slaves, actually scarcely considered by the medicine of that time. The Industrial Revolution caused an epidemic of metal intoxication, urging scientists and physician of that period to study and identify specific symptoms and organ alterations related to chronic lead poisoning. During the 20th century, the acknowledgment of occupational and environmental toxicity of lead fostered public awareness and legislation to protect health. More recently, the identification of sub-clinical effects have greatly modified the concept of lead poisoning and the approaches of medicine towards this condition. Nowadays, lead poisoning is rarely seen in developed countries, but it still represents a major environmental problem in certain areas. Consequently, it may appear as a paradigm of "occupational and environmental disease," and the history of this condition seems to parallel the historical development of modern "Occupational and Environmental Health" as a more complete medical discipline.
Keywords: History; Lead poisoning; Occupational health.
Conflict of interest statement
No potential conflict of interest relevant to this article was reported.
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References
-
- Riva MA, Sironi VA, Fano D, Cesana G. Workers' health conditions in the Greco-Roman world: the contribution of non-medical sources. Arch Environ Occup Health. 2011;66:54–55. - PubMed
-
- Gochfeld M. Chronologic history of occupational medicine. J Occup Environ Med. 2005;47:96–114. - PubMed
-
- Bertazzi PA. Work as a basic human need and health promoting factor. Med Lav. 2010;101(Suppl 2):28–43. Italian. - PubMed
-
- Rosen G. A history of public health. Expanded ed. Baltimore (MD): Johns Hopkins University Press; 1993. p. 535.
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