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Case Reports
. 1998 Dec;29(4):456-60.

Disseminated histoplasmosis in an Atlantic bottlenose dolphin (Tursiops truncatus)

E D Jensen  1 , T Lipscomb, B Van Bonn, G Miller, J M Fradkin, S H Ridgway
Affiliations
  • PMID: 10065856
Case Reports

Disseminated histoplasmosis in an Atlantic bottlenose dolphin (Tursiops truncatus)

E D Jensen et al. J Zoo Wildl Med. 1998 Dec.

Abstract

An approximately 37-yr-old female Atlantic bottlenose dolphin (Tursiops truncatus) died after a 4-mo illness characterized by intermittent anorexia, lethargy, mild neutrophilic leukocytosis, and mild nonregenerative anemia. At necropsy, the lungs were diffusely consolidated, and histopathology of the lungs revealed severe pneumonia with macrophages containing clusters of numerous yeast cells. Inflammatory lesions and yeast also were found in pulmonary, mediastinal, prescapular, and duodenal lymph nodes, spleen, liver, kidneys, urinary bladder, pancreas, right adrenal gland, and the pyloric stomach. Histomorphology, fungal culture, and polymerase chain reaction analysis indicated that the fungus was Histoplasma capsulatum var. capsulatum. This is the first report of histoplasmosis in a cetacean.

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