A samurai sword dating from the 15th century was among the artefacts abandoned by the departing inhabitants of the former Earth colony Jegg-Sau in the 25th century. (AUDIO: The Relics of Jegg-Sau)

The First Doctor, Susan Foreman, Ian Chesterton, and Barbara Wright visited the Aztec empire. Barbara, taken for the reincarnation of Yetaxa, tried in vain to stop the Aztec practice of human sacrifice. (TV: The Aztecs)

By the 15th century, it was against Spanish custom to engage in the slave trade. (AUDIO: Trouble in Paradise)

In the mid-15th century, the Scottish Border Wars were fought between Scotland and England. (PROSE: Iris at the V&A)

As with most centuries of the first two millennia, the 15th century was home to Jack Harkness, Amy Pond and an Auton duplicate of Rory Williams. A version of Jack from around the time of the deaths of Toshiko Sato and Owen Harper existed in this century, having been buried alive in the 1st century by his brother, Gray. He perpetually died and resurrected an unknown number of times in an earthen tomb underneath Cardiff. (TV: Exit Wounds) Meanwhile, a near-dead Amy Pond was kept alive inside the Pandorica, beginning in the 2nd century. An Auton version of Rory kept vigil near her the entire time. They both awaited a moment in the mid-1990s when a young Amelia Pond would touch the outside of the Pandorica and restore Amy to full health. (TV: The Big Bang)

It was substantially unclear whether the events of the subsequent Big Bang Two erased Amy and Rory's presence in the 15th century. This ambiguity was caused, in part, because the non-Auton, married Rory Williams claimed to have remembered being "made of plastic" at his wedding reception, suggesting that, at least inasmuch as he was concerned, he and Amy were present in the 15th century. (TV: The Big Bang) Amy seemed to also remember those events, and displayed a fondness for the Auton Rory both during her honeymoon (TV: A Christmas Carol) and during a kind of lullaby to her newborn child Melody Pond. (TV: A Good Man Goes to War)

It was also among the centuries endured by Ashildr, (TV: The Woman Who Lived) a 9th century^[1] Viking girl who was rendered effectively immortal when she was brought back to life by the Twelfth Doctor through a self-repairing Mire repair kit. (TV: The Girl Who Died)

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