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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1948 1
1951 2
1953 1
1954 2
1955 3
1957 1
1958 2
1959 1
1960 6
1961 5
1962 10
1963 7
1964 11
1965 8
1967 2
1969 1
1970 5
1971 69
1972 214
1973 171
1974 191
1975 243
1976 276
1977 442
1978 487
1979 523
1980 636
1981 707
1982 855
1983 878
1984 935
1985 1076
1986 1098
1987 1118
1988 1362
1989 1585
1990 1964
1991 2278
1992 2536
1993 3061
1994 3571
1995 3268
1996 3591
1997 4036
1998 4588
1999 5212
2000 5991
2001 6378
2002 5815
2003 6059
2004 5408
2005 4077
2006 3497
2007 2954
2008 2985
2009 3278
2010 3077
2011 3041
2012 3255
2013 3605
2014 3336
2015 3525
2016 2929
2017 2787
2018 2543
2019 2122
2020 1950
2021 1862
2022 1741
2023 1504
2024 1174
2025 17

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Page 1
Structure of the nutrient-sensing hub GATOR2.
Valenstein ML, Rogala KB, Lalgudi PV, Brignole EJ, Gu X, Saxton RA, Chantranupong L, Kolibius J, Quast JP, Sabatini DM. Valenstein ML, et al. Nature. 2022 Jul;607(7919):610-616. doi: 10.1038/s41586-022-04939-z. Epub 2022 Jul 13. Nature. 2022. PMID: 35831510 Free PMC article.
Interleukin-18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis.
Knorr J, Kaufmann B, Inzaugarat ME, Holtmann TM, Geisler L, Hundertmark J, Kohlhepp MS, Boosheri LM, Chilin-Fuentes DR, Birmingham A, Fisch KM, Schilling JD, Loosen SH, Trautwein C, Roderburg C, Demir M, Tacke F, Hoffman HM, Feldstein AE, Wree A. Knorr J, et al. Hepatology. 2023 Jun 1;77(6):1968-1982. doi: 10.1002/hep.32776. Epub 2022 Oct 12. Hepatology. 2023. PMID: 36059147 Free PMC article.
TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson's disease.
Seo BA, Kim D, Hwang H, Kim MS, Ma SX, Kwon SH, Kweon SH, Wang H, Yoo JM, Choi S, Kwon SH, Kang SU, Kam TI, Kim K, Karuppagounder SS, Kang BG, Lee S, Park H, Kim S, Yan W, Li YS, Kuo SH, Redding-Ochoa J, Pletnikova O, Troncoso JC, Lee G, Mao X, Dawson VL, Dawson TM, Ko HS. Seo BA, et al. Neuron. 2021 Dec 1;109(23):3758-3774.e11. doi: 10.1016/j.neuron.2021.09.031. Epub 2021 Oct 12. Neuron. 2021. PMID: 34644545 Free PMC article.
Genetics of the human microglia regulome refines Alzheimer's disease risk loci.
Kosoy R, Fullard JF, Zeng B, Bendl J, Dong P, Rahman S, Kleopoulos SP, Shao Z, Girdhar K, Humphrey J, de Paiva Lopes K, Charney AW, Kopell BH, Raj T, Bennett D, Kellner CP, Haroutunian V, Hoffman GE, Roussos P. Kosoy R, et al. Nat Genet. 2022 Aug;54(8):1145-1154. doi: 10.1038/s41588-022-01149-1. Epub 2022 Aug 5. Nat Genet. 2022. PMID: 35931864 Free PMC article.
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