SM-Youtube

1

Role of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage.

Yoshida K, Miki Y. Yoshida K, et al. Cancer Sci. 2004 Nov;95(11):866-71. doi: 10.1111/j.1349-7006.2004.tb02195.x. Cancer Sci. 2004. PMID: 15546503 Free PMC article. Review.

2

Activation of SAPK/JNK signaling by protein kinase Cdelta in response to DNA damage.

Yoshida K, Miki Y, Kufe D. Yoshida K, et al. J Biol Chem. 2002 Dec 13;277(50):48372-8. doi: 10.1074/jbc.M205485200. Epub 2002 Oct 10. J Biol Chem. 2002. PMID: 12377781 Free article.

3

Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9.

Yoshida K, Wang HG, Miki Y, Kufe D. Yoshida K, et al. EMBO J. 2003 Mar 17;22(6):1431-41. doi: 10.1093/emboj/cdg134. EMBO J. 2003. PMID: 12628935 Free PMC article.

4

JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage.

Yoshida K, Yamaguchi T, Natsume T, Kufe D, Miki Y. Yoshida K, et al. Nat Cell Biol. 2005 Mar;7(3):278-85. doi: 10.1038/ncb1228. Nat Cell Biol. 2005. PMID: 15696159

5

Enabling death by the Abl tyrosine kinase: mechanisms for nuclear shuttling of c-Abl in response to DNA damage.

Yoshida K, Miki Y. Yoshida K, et al. Cell Cycle. 2005 Jun;4(6):777-9. doi: 10.4161/cc.4.6.1746. Epub 2005 Jun 14. Cell Cycle. 2005. PMID: 15917667

6

Protein kinase C delta regulates Ser46 phosphorylation of p53 tumor suppressor in the apoptotic response to DNA damage.

Yoshida K, Liu H, Miki Y. Yoshida K, et al. J Biol Chem. 2006 Mar 3;281(9):5734-40. doi: 10.1074/jbc.M512074200. Epub 2005 Dec 23. J Biol Chem. 2006. PMID: 16377624 Free article.

7

Protein kinase C delta activates topoisomerase IIalpha to induce apoptotic cell death in response to DNA damage.

Yoshida K, Yamaguchi T, Shinagawa H, Taira N, Nakayama KI, Miki Y. Yoshida K, et al. Mol Cell Biol. 2006 May;26(9):3414-31. doi: 10.1128/MCB.26.9.3414-3431.2006. Mol Cell Biol. 2006. PMID: 16611985 Free PMC article.

8

PKCdelta signaling: mechanisms of DNA damage response and apoptosis.

Yoshida K. Yoshida K. Cell Signal. 2007 May;19(5):892-901. doi: 10.1016/j.cellsig.2007.01.027. Epub 2007 Feb 7. Cell Signal. 2007. PMID: 17336499 Review.

9

DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage.

Taira N, Nihira K, Yamaguchi T, Miki Y, Yoshida K. Taira N, et al. Among authors: yoshida k. Mol Cell. 2007 Mar 9;25(5):725-38. doi: 10.1016/j.molcel.2007.02.007. Mol Cell. 2007. PMID: 17349958 Free article.

10

Protein kinase C delta activates IkappaB-kinase alpha to induce the p53 tumor suppressor in response to oxidative stress.

Yamaguchi T, Miki Y, Yoshida K. Yamaguchi T, et al. Among authors: yoshida k. Cell Signal. 2007 Oct;19(10):2088-97. doi: 10.1016/j.cellsig.2007.06.002. Epub 2007 Jun 21. Cell Signal. 2007. PMID: 17644309

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