doi: 10.1006/geno.1993.1257.
Mapping genes according to their amplification status in tumor cells: contribution to the map of 11q13
Affiliations
- PMID: 8325649
- DOI: 10.1006/geno.1993.1257
Item in Clipboard
Mapping genes according to their amplification status in tumor cells: contribution to the map of 11q13
Genomics.
1993 Jun.
Abstract
DNA amplification events that occur at 11q13 in human carcinomas are complex, and amplicons were shown to exhibit numerous discontinuities that could be used as tools for mapping this genomic area. A statistical nearest-neighbor analysis of the amplification patterns of several 11q13 loci in a panel of amplified DNAs was performed in the region of 11q13 centromeric from BCL1. It was strongly correlated with the physical linkages that we established between the same markers. Taken together, our results led to a map of 14 genes and four anonymous probes located in this area.
Similar articles
-
Amplification of 11q13 DNA sequences in human breast cancer: D11S97 identifies a region tightly linked to BCL1 which can be amplified separately.Oncogene. 1992 Apr;7(4):751-5. Oncogene. 1992. PMID: 1565470
-
D11S146 and BCL1 are physically linked but can be discriminated by their amplification status in human breast cancer.Genomics. 1991 Jun;10(2):410-6. doi: 10.1016/0888-7543(91)90326-a. Genomics. 1991. PMID: 2071147
-
DNA amplification at 11q13.5-q14 in human breast cancer.Oncogene. 1992 Dec;7(12):2513-7. Oncogene. 1992. PMID: 1461654
-
Chromosome 11q13 markers and D-type cyclins in breast cancer.Breast Cancer Res Treat. 1995;33(2):125-35. doi: 10.1007/BF00682720. Breast Cancer Res Treat. 1995. PMID: 7749140 Review.
-
Chromosome 11q13 abnormalities in human breast cancer.Cancer Surv. 1993;18:77-94. Cancer Surv. 1993. PMID: 8013002 Review.
Cited by
-
Expression and gene amplification of primary (A, B1, D1, D3, and E) and secondary (C and H) cyclins in colon adenocarcinomas and correlation with patient outcome.J Clin Pathol. 2005 May;58(5):509-14. doi: 10.1136/jcp.2004.020347. J Clin Pathol. 2005. PMID: 15858123 Free PMC article.
-
Genetic mapping studies of 40 loci and 23 cosmids in chromosome 11p13-11q13, and exclusion of mu-calpain as the multiple endocrine neoplasia type 1 gene.Hum Genet. 1996 Jun;97(6):732-41. doi: 10.1007/BF02346182. Hum Genet. 1996. PMID: 8641689
-
Induction of t(11;14) IgH enhancer/promoter-cyclin D1 gene translocation using CRISPR/Cas9.Oncol Lett. 2019 Jul;18(1):275-282. doi: 10.3892/ol.2019.10303. Epub 2019 May 2. Oncol Lett. 2019. PMID: 31289497 Free PMC article.
-
Human EMK1 is located on 11q12-q13, close to COX8 and FTH1.Mamm Genome. 1995 Apr;6(4):311-2. doi: 10.1007/BF00352433. Mamm Genome. 1995. PMID: 7613050 No abstract available.
-
High-resolution mapping of the 11q13 amplicon and identification of a gene, TAOS1, that is amplified and overexpressed in oral cancer cells.Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11369-74. doi: 10.1073/pnas.172285799. Epub 2002 Aug 9. Proc Natl Acad Sci U S A. 2002. PMID: 12172009 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
Research Materials
