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Review
. 2023 May 6;11(13):2903-2915.
doi: 10.12998/wjcc.v11.i13.2903.

Clinical management of dural defects: A review

Rong-Peng Dong  1 , Qi Zhang  1 , Li-Li Yang  1 , Xue-Liang Cheng  1 , Jian-Wu Zhao  2
Affiliations
Review

Clinical management of dural defects: A review

Rong-Peng Dong et al. World J Clin Cases. .

Abstract

Dural defects are common in spinal and cranial neurosurgery. A series of complications, such as cerebrospinal fluid leakage, occur after rupture of the dura. Therefore, treatment strategies are necessary to reduce or avoid complications. This review comprehensively summarizes the common causes, risk factors, clinical complications, and repair methods of dural defects. The latest research progress on dural repair methods and materials is summarized, including direct sutures, grafts, biomaterials, non-biomaterial materials, and composites formed by different materials. The characteristics and efficacy of these dural substitutes are reviewed, and these materials and methods are systematically evaluated. Finally, the best methods for dural repair and the challenges and future prospects of new dural repair materials are discussed.

Keywords: Causes of dural defect; Cerebrospinal fluid leak; Dural defect; Dural repair; Incidental durotomy.

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Conflict of interest statement

Conflict-of-interest statement: Authors declare no conflict of interests for this article.

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References

    1. Alshameeri ZAF, Jasani V. Risk Factors for Accidental Dural Tears in Spinal Surgery. Int J Spine Surg. 2021;15:536–548. - PMC - PubMed
    1. Ishikura H, Ogihara S, Oka H, Maruyama T, Inanami H, Miyoshi K, Matsudaira K, Chikuda H, Azuma S, Kawamura N, Yamakawa K, Hara N, Oshima Y, Morii J, Saita K, Tanaka S, Yamazaki T. Risk factors for incidental durotomy during posterior open spine surgery for degenerative diseases in adults: A multicenter observational study. PLoS One. 2017;12:e0188038. - PMC - PubMed
    1. Kamenova M, Leu S, Mariani L, Schaeren S, Soleman J. Management of Incidental Dural Tear During Lumbar Spine Surgery. To Suture or Not to Suture? World Neurosurg. 2016;87:455–462. - PubMed
    1. Choi EH, Chan AY, Brown NJ, Lien BV, Sahyouni R, Chan AK, Roufail J, Oh MY. Effectiveness of Repair Techniques for Spinal Dural Tears: A Systematic Review. World Neurosurg. 2021;149:140–147. - PMC - PubMed
    1. Bi X, Liu B, Mao Z, Wang C, Dunne N, Fan Y, Li X. Applications of materials for dural reconstruction in pre-clinical and clinical studies: Advantages and drawbacks, efficacy, and selections. Mater Sci Eng C Mater Biol Appl. 2020;117:111326. - PubMed