The Evolution of Antiviral Defense Systems
- PMID: 26867173
- DOI: 10.1016/j.chom.2016.01.006
The Evolution of Antiviral Defense Systems
Abstract
Self-replicating genetic material presumably provided the architecture necessary for generating the last universal ancestor of all nucleic-acid-based life. As biological complexity increased in the billions of years that followed, the same genetic material also morphed into a wide spectrum of viruses and other parasitic genetic elements. The resulting struggle for existence drove the evolution of host defenses, giving rise to a perpetual arms race. This Perspective summarizes the antiviral mechanisms evident across the tree of life, discussing each in their evolutionary context to postulate how the coevolution of host and pathogen shaped the cellular antiviral defenses we know today.
Copyright © 2016 Elsevier Inc. All rights reserved.
Similar articles
-
Paleovirology and virally derived immunity.Trends Ecol Evol. 2012 Nov;27(11):627-36. doi: 10.1016/j.tree.2012.07.007. Epub 2012 Aug 14. Trends Ecol Evol. 2012. PMID: 22901901 Review.
-
A virocentric perspective on the evolution of life.Curr Opin Virol. 2013 Oct;3(5):546-57. doi: 10.1016/j.coviro.2013.06.008. Epub 2013 Jul 12. Curr Opin Virol. 2013. PMID: 23850169 Free PMC article. Review.
-
[Progress in studies of viperin, an important cellular antiviral factor].Bing Du Xue Bao. 2015 Jan;31(1):91-6. Bing Du Xue Bao. 2015. PMID: 25997337 Review. Chinese.
-
Interferons and microRNAs.J Interferon Cytokine Res. 2010 Nov;30(11):825-8. doi: 10.1089/jir.2010.0080. Epub 2010 Oct 12. J Interferon Cytokine Res. 2010. PMID: 20939680 Review.
-
Virus-Host Coevolution with a Focus on Animal and Human DNA Viruses.J Mol Evol. 2020 Jan;88(1):41-56. doi: 10.1007/s00239-019-09913-4. Epub 2019 Oct 10. J Mol Evol. 2020. PMID: 31599342 Free PMC article. Review.
Cited by
-
siRNA Functionalized Lipid Nanoparticles (LNPs) in Management of Diseases.Pharmaceutics. 2022 Nov 19;14(11):2520. doi: 10.3390/pharmaceutics14112520. Pharmaceutics. 2022. PMID: 36432711 Free PMC article. Review.
-
Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling.bioRxiv [Preprint]. 2020 May 27:2020.05.27.118893. doi: 10.1101/2020.05.27.118893. bioRxiv. 2020. Update in: J Exp Med. 2020 Dec 7;217(12):e20201241. doi: 10.1084/jem.20201241 PMID: 32577647 Free PMC article. Updated. Preprint.
-
The Kinase IKKβ Regulates a STING- and NF-κB-Dependent Antiviral Response Pathway in Drosophila.Immunity. 2018 Aug 21;49(2):225-234.e4. doi: 10.1016/j.immuni.2018.07.013. Epub 2018 Aug 14. Immunity. 2018. PMID: 30119996 Free PMC article.
-
What viruses tell us about evolution and immunity: beyond Darwin?Ann N Y Acad Sci. 2019 Jul;1447(1):53-68. doi: 10.1111/nyas.14097. Epub 2019 Apr 29. Ann N Y Acad Sci. 2019. PMID: 31032941 Free PMC article. Review.
-
Visualization of RNA virus infection in a marine protist with a universal biomarker.Sci Rep. 2023 Apr 10;13(1):5813. doi: 10.1038/s41598-023-31507-w. Sci Rep. 2023. PMID: 37037845 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Research Materials
