Comparative Study
Controversies in the treatment of streptococcal pharyngitis
Affiliations
- PMID: 2244548
Item in Clipboard
Comparative Study
Controversies in the treatment of streptococcal pharyngitis
Am Fam Physician.
1990 Dec.
Abstract
An increasing number of cases of sore throat caused by group A beta-hemolytic streptococci occur with concomitant colonization by organisms that may "protect" the streptococci through beta-lactamase inactivation of penicillin at the site of infection. The failure of penicillin to eradicate many of these bacteria, which include Staphylococcus aureus, Haemophilus influenzae, Moraxella (Branhamella) catarrhalis and a multitude of pharyngeal anaerobes, may help to explain why penicillin is sometimes ineffective for acute and recurrent group A streptococcal infections. Therapeutic alternatives currently include cephalosporins, erythromycin, rifampin combined with penicillin, amoxicillin/clavulanate potassium and others.
Comment in
-
Streptococcal pharyngitis.Am Fam Physician. 1991 Aug;44(2):402, 404, 406. Am Fam Physician. 1991. PMID: 1907084 No abstract available.
-
Streptococcal pharyngitis.Am Fam Physician. 1990 Dec;42(6):1558-60. Am Fam Physician. 1990. PMID: 2244547 No abstract available.
Similar articles
-
[Significance of normal oropharyngeal flora in the development of streptococcal pharyngitis and outcome of penicillin therapy].Med Pregl. 1998 May-Jun;51(5-6):275-8. Med Pregl. 1998. PMID: 9720358 Croatian.
-
Penicillin failure and copathogenicity in streptococcal pharyngotonsillitis.J Fam Pract. 1994 Feb;38(2):175-9. J Fam Pract. 1994. PMID: 8308510 Review.
-
Overcoming penicillin failures in the treatment of Group A streptococcal pharyngo-tonsillitis.Int J Pediatr Otorhinolaryngol. 2007 Oct;71(10):1501-8. doi: 10.1016/j.ijporl.2007.06.006. Epub 2007 Jul 17. Int J Pediatr Otorhinolaryngol. 2007. PMID: 17644191 Review.
-
Group A streptococcal tonsillopharyngitis: cost-effective diagnosis and treatment.Ann Emerg Med. 1995 Mar;25(3):390-403. doi: 10.1016/s0196-0644(95)70300-4. Ann Emerg Med. 1995. PMID: 7864482 Review.
-
[Antibiotic treatment of pharyngitis].Ann Pediatr (Paris). 1991 Oct;38(8):545-8. Ann Pediatr (Paris). 1991. PMID: 1746852 Review. French.
Cited by
-
Cost saving of 5-day therapy with cefpodoxime proxetil versus standard 10-day beta-lactam therapy for recurrent pharyngotonsillitis in adults. A prospective general practice study.Pharmacoeconomics. 1996 Sep;10(3):239-50. doi: 10.2165/00019053-199610030-00005. Pharmacoeconomics. 1996. PMID: 10172792 Clinical Trial.
-
Are antibiotics appropriate for sore throats? Careful prescribing is beneficial.BMJ. 1994 Oct 15;309(6960):1011-2. doi: 10.1136/bmj.309.6960.1011. BMJ. 1994. PMID: 7950696 Free PMC article. Review. No abstract available.
-
Redefining the management of pediatric tonsillopharyngitis with cefprozil.Indian J Pediatr. 2007 Dec;74(12):1105-8. doi: 10.1007/s12098-007-0206-8. Indian J Pediatr. 2007. PMID: 18174646 Review.
-
Streptococcus pyogenes pharyngitis: characterization of strains by multilocus enzyme genotype, M and T protein serotype, and pyrogenic exotoxin gene probing.J Clin Microbiol. 1992 Mar;30(3):600-3. doi: 10.1128/jcm.30.3.600-603.1992. J Clin Microbiol. 1992. PMID: 1551976 Free PMC article.
-
Comparative efficacy and safety of cefprozil versus penicillin, cefaclor and erythromycin in the treatment of streptococcal pharyngitis and tonsillitis.Eur J Clin Microbiol Infect Dis. 1994 Oct;13(10):846-50. doi: 10.1007/BF02111351. Eur J Clin Microbiol Infect Dis. 1994. PMID: 7889958 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Medical