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Review
. 2009 Sep-Oct;1(5):422-31.
doi: 10.4161/mabs.1.5.9286. Epub 2009 Sep 15.

Golimumab

Sohini Mazumdar  1 , David Greenwald
Affiliations
Review

Golimumab

Sohini Mazumdar et al. MAbs. 2009 Sep-Oct.

Abstract

Golimumab, a human anti-TNFalpha IgG1kappa monoclonal antibody, was approved in the US and Canada in April 2009 as a treatment for rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis, and is undergoing regulatory review in the EU for these indications. The product was developed by Centocor and Janssen Pharmaceutical KK (Johnson & Johnson subsidiaries), in collaboration with Schering-Plough and Mitsubishi Tanabe Pharma. Golimumab faces numerous protein therapeutic competitors on the market, but, as the first patient-administered, once-monthly dosed anti-TNFalpha drug, it will likely be an attractive option for patients.

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Figures

Table 1
Table 1
Clinical studies in approved indications: Rheumatoid arthritis
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