The USS Reprisal (NCC-1605) was a Federation starship, a Constitution-class heavy cruiser in service to Starfleet in the late 23rd century. In particular, the Reprisal was a refit ship of the Enterprise-subclass, specifically outfitted as a heavy drone cruiser (CAD) by the 2280s decade. The ship was easily modifiable with additional technology to become a rear-fire heavy drone cruiser (CADR) or the advanced heavy drone cruiser (CAD+). (ST video game: Starfleet Command)
- No history or fate is established for this vessel in Starfleet Command as its name was randomly assigned to a cruiser vessel by the game software.