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Summary

Description
English: In sickle cell anemia, the Thymine nucleotide base on the DNA template strand is replaced with Adenine, which causes the mRNA to have a Uracil nucleotide instead of an Adenine one. This carries forward and during translation, instead of glutamic acid being added, a valine amino acid is instead added to the chain of amino acids. This makes the hemoglobin molecule prone to polymerisation when deoxygenated, giving the affected cell a sickle shape.
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Author MapleDragon123

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Captions

Base-pair substitution that causes sickle cell anemia

18 May 2022

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current16:31, 18 May 2022Thumbnail for version as of 16:31, 18 May 2022512 × 384 (118 KB)MapleDragon123Uploaded own work with UploadWizard

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